SCHEMBL4199390

SCHEMBL4199390

O=C1Nc2cccc3cccc(c23)N1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAD52 P43351 1/20 0.52
▸ KMT2A Q03164 8/20 0.52
▸ MAPT P10636 8/20 0.50
▸ MEN1 O00255 7/20 0.50
▸ ALDH1A1 P00352 6/20 0.50
▸ GAA P10253 6/20 0.50
▸ KDM4E B2RXH2 4/20 0.50
▸ APAF1 O14727 3/20 0.50
▸ L3MBTL1 Q9Y468 3/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ PARP1 P09874 1/20 0.48
▸ NR4A1 P22736 3/20 0.45
▸ HPGD P15428 3/20 0.45
▸ HSD17B10 Q99714 3/20 0.45
▸ USP2 O75604 3/20 0.45
▸ TSHR P16473 2/20 0.45
▸ APP P05067 1/20 0.45
▸ SNCA P37840 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ POLB P06746 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412557 1.00 RAD52 (0.52) RAD52KMT2AMAPTMEN1ALDH1A1
Urea SCHEMBL6442362 0.88 ALDH1A1 (0.53) RAD52KMT2AMAPTMEN1ALDH1A1
SCHEMBL14559393 0.75 ACVR1 (0.52) KMT2AMAPTMEN1GAANPC1
SCHEMBL315397 0.75 RAD52 (0.52) RAD52KMT2AMAPTMEN1ALDH1A1
SCHEMBL4155254 0.75 RAD52 (0.52) RAD52KMT2AMAPTMEN1ALDH1A1
SCHEMBL302763 0.75 PARP1 (0.72) KMT2AMAPTALDH1A1GAAL3MBTL1
SCHEMBL29428940 0.75 PARP1 (0.72) KMT2AMAPTALDH1A1GAAL3MBTL1
SCHEMBL27936606 0.74 ALDH1A1 (0.53) RAD52KMT2AMAPTMEN1ALDH1A1
SCHEMBL28498212 0.73 RAD52 (0.54) RAD52KMT2AMAPTMEN1ALDH1A1
SCHEMBL30736009 0.72 AHR (0.64) KMT2AMAPTMEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11753426-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and organic light-emitting apparatus including the organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 — — US disclosed
US-11753426-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and organic light-emitting apparatus including the organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 — — US disclosed
WO-2022135355-A1 METHOD FOR CATALYTICALLY ACTIVATING CARBON DIOXIDE AS CARBONYLATION REAGENT WITH INORGANIC SULFUR 内蒙古工业大学 2022-06-30 — — WO disclosed
US-20200319548-A1 COMPOSITION, FILM, NEAR INFRARED CUT FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND INFRARED SENSOR FUJIFILM CORPORATION (JP) 2020-10-08 — — US disclosed
US-20190263849-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND ORGANIC LIGHT-EMITTING APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-29 — — US disclosed
US-8449989-B2 Organic compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2013-05-28 — — US disclosed
US-8449989-B2 Organic compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2013-05-28 — — US disclosed
US-8449989-B2 Organic compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2013-05-28 — — US disclosed
EP-1680479-B1 NEW ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2012-11-28 — — EP disclosed
US-20090121622-A1 NEW ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD (KR) 2009-05-14 — — US disclosed
US-20090121622-A1 NEW ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD (KR) 2009-05-14 — — US disclosed
US-7455917-B2 Organic compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2008-11-25 — — US disclosed
US-7455917-B2 Organic compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2008-11-25 — — US disclosed
US-7455917-B2 Organic compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2008-11-25 — — US disclosed
EP-1680479-A1 NEW ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG Chem, Ltd. (KR) 2006-07-19 — — EP disclosed
US-20060130565-A1 Measurement of total reactive isocyanate groups in samples using bifunctional nucleophiles such as 1,8-diaminonaphthalene (dan) THE UNIVERSITY OF MASSACHUSETTS LOWELL RESEARCH FOUNDATION 2006-06-22 — — US disclosed
EP-1579207-A2 MEASUREMENT OF TOTAL REACTIVE ISOCYANATE GROUPS IN SAMPLES USING BIFUNCTIONAL NUCLEOPHILES SUCH AS 1,8-DIAMINONAPHTHALENE (DAN) The Government of the United States of America, as represented by the Secretary, Department of Health & Human Services (US) 2005-09-28 — — EP disclosed
US-20050123800-A1 Organic compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2005-06-09 — — US disclosed
WO-2005037954-A1 NEW ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD. (KR) 2005-04-28 — — WO disclosed
WO-2004051221-A2 MEASUREMENT OF TOTAL REACTIVE ISOCYANATE GROUPS IN SAMPLES USING BIFUNCTIONAL NUCLEOPHILES SUCH AS 1,8-DIAMINONAPHTHALENE (DAN) THE GOVERNMENT OF THE UNITED STATES OF AMERICA (US) 2004-06-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190263849-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND ORGANIC LIGHT-EMITTING APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, L3MBTL1, MSL1 RAD52 1325/4885KMT2A 1255/4885MAPT 867/4885
US-11753426-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and organic light-emitting apparatus including the organic light-emitting device L1CAM, L3MBTL1, MSL1 RAD52 1325/4885KMT2A 1255/4885MAPT 867/4885
US-20050123800-A1 Organic compound and organic light emitting device using the same LEF1, CYBA, AOX1 RAD52 3606/4885KMT2A 3932/4885MAPT 1317/4885
US-20090121622-A1 NEW ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LEF1, CYBA, AOX1 RAD52 3263/4885KMT2A 4057/4885MAPT 1255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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