SCHEMBL6442833

SCHEMBL6442833

COc1ccccc1/C=N\C(C)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 4/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HSD17B10 Q99714 1/20 0.41
GAA P10253 3/20 0.41
RAB9A P51151 2/20 0.41
PKM P14618 1/20 0.41
MAPT P10636 4/20 0.40
CYP1A2 P05177 3/20 0.40
CYP3A4 P08684 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6442838 1.00 GRIN2D (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6446544 0.90 GAA (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6445990 0.85 ALDH1A1 (0.49) KMT2AALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6448723 0.85 LMNA (0.47) MEN1KMT2AALDH1A1HPGDSMN1; SMN2
SCHEMBL6445991 0.85 ALDH1A1 (0.49) KMT2AALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6445987 0.85 ALDH1A1 (0.49) KMT2AALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6445689 0.85 ANO1 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6442353 0.82 ANO1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6442356 0.82 ANO1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6442986 0.81 GAA (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6894190-B2 Process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-17 US disclosed