Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160757 | 0.89 | MAPT (0.49) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL1857696 | 0.87 | PPARA (0.59) | PPARA | |
| SCHEMBL5659791 | 0.87 | PPARA (0.59) | PPARA | |
| SCHEMBL27357477 | 0.86 | MAPT (0.47) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL1860936 | 0.86 | LMNA (0.47) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL2672728 | 0.84 | MAPT (0.59) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL5160654 | 0.82 | MAPT (0.51) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL5160644 | 0.82 | MAPT (0.51) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL8259986 | 0.82 | MAPT (0.51) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL2554435 | 0.82 | PPARA (0.52) | PPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096331-A1 | Novel compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES INC. | 2005-05-05 | — | — | US | disclosed |
| WO-2003053974-A1 | NOVEL COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096331-A1 | Novel compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them | GPR119, LIPA, CETP | MAPT 221/4885CRHBP 3541/4885CRHR2 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.