SCHEMBL6443427

SCHEMBL6443427

CC1=C2c3cn(-c4ccccc4)cc3C1[Si]2(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5948736 0.84
Hydrochloric Acid SCHEMBL5948565 0.83
Hydrochloric Acid SCHEMBL2511758 0.76
SCHEMBL6445950 0.68 ALDH1A1 (0.36)
SCHEMBL21115362 0.63 ALDH1A1 (0.36)
SCHEMBL720718 0.62 NPC1 (0.41)
SCHEMBL4791698 0.61 TUBB4A (0.44)
SCHEMBL24311360 0.60 TUBB4A (0.48)
SCHEMBL6455046 0.60
SCHEMBL17916171 0.58 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed
US-6949614-B1 Catalyst system BASELL POLYOLEFINE GMBH (DE) 2005-09-27 US disclosed
EP-1272532-B1 SALINE CHEMICAL COMPOSITION, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2005-05-04 EP disclosed
EP-1054914-B1 ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND BASELL POLYOLEFINE GMBH (DE) 2004-03-03 EP disclosed
EP-1175262-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2004-02-18 EP disclosed
EP-1290002-B1 CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-01-21 EP disclosed