Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2164875 | 0.89 | TSHR (0.39) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30881973 | 0.89 | TSHR (0.39) | CA1CA2CA7CA9CA12 | |
| SCHEMBL6445429 | 0.81 | NQO1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL29435933 | 0.80 | CA1 (0.62) | CA1CA2CA7CA9CA12 | |
| SCHEMBL625622 | 0.80 | CA1 (0.62) | CA1CA2CA7CA9CA12 | |
| SCHEMBL6296270 | 0.79 | TSHR (0.39) | ALDH1A1L3MBTL1MAPK1KMT2AKDM4E | |
| SCHEMBL3724176 | 0.79 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1MAPTTDP1CYP1A2 | |
| SCHEMBL13141612 | 0.78 | TDP1 (0.40) | CA2ALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL7524628 | 0.77 | TSHR (0.39) | ALDH1A1L3MBTL1MAPK1HTTMAPT | |
| SCHEMBL14388549 | 0.77 | TSHR (0.36) | ALDH1A1L3MBTL1MAPK1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893444-B1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-5936102-A | CYCLOCONDENSING O-(2-BROMOTETRAFLUOROETHOXY)PHENOL IN THE PRESENCE OF ACID BINDER | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-10 | — | — | US | disclosed |
| EP-0893444-A1 | Process for reparing 2,2,3,3-tetrafluoro-1,4-benzodioxanes, new o-(2-bromo-1,1,2,2,-tetrafluoroethoxy)-phenols and new2-bromo-1,1,2,2-tetrafuoroethoxy-phenylethers | BAYER AG (DE) | 1999-01-27 | — | — | EP | disclosed |