SCHEMBL3724176

SCHEMBL3724176

CCOc1ccccc1OC(F)(F)C(F)F

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 1/20 0.45
MAPT P10636 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GLA P06280 1/20 0.44
ALOX15 P16050 1/20 0.42
PDK2 Q15119 1/20 0.41
AR P10275 1/20 0.40
HCRTR1 O43613 2/20 0.40
HTR1A P08908 1/20 0.38
ADRA1D P25100 1/20 0.38
ADRA1A P35348 1/20 0.38
ADRA1B P35368 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30881973 0.84 TSHR (0.39) L3MBTL1TDP1ALDH1A1MAPTNPSR1
SCHEMBL2164875 0.84 TSHR (0.39) L3MBTL1TDP1ALDH1A1MAPTNPSR1
SCHEMBL10852468 0.79 RXRA (0.54) L3MBTL1TDP1MAPTHTR1AADRA1D
SCHEMBL6443536 0.79 CA1 (0.54) L3MBTL1CYP1A2TDP1ALDH1A1MAPT
1,2-Diethoxybenzene SCHEMBL578986 0.77 ALDH1A1 (0.68) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
1,2-Diethoxybenzene SCHEMBL29428929 0.77 ALDH1A1 (0.68) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL3724179 0.76 L3MBTL1 (0.46) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL11974099 0.76 ALDH1A1 (0.52) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL7524628 0.76 TSHR (0.39) L3MBTL1TDP1ALDH1A1MAPTNPSR1
SCHEMBL12868106 0.76 AR (0.41) L3MBTL1CYP1A2CYP2C19ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465850-B2 Method for the application of active materials onto a surface and devices made with such methods E I DU PONT DE NEMOURS AND COMPANY (US) 2013-06-18 US disclosed
US-8465850-B2 Method for the application of active materials onto a surface and devices made with such methods E I DU PONT DE NEMOURS AND COMPANY (US) 2013-06-18 US disclosed
US-8287766-B2 depositing fluorinated aryl ethers and polyanilines or polythiophenes combined with fluorinated polysulfonic acids and/or mixtures, onto glass substrates, useful in organic electronic devices; organic light emitting diodes E I DU PONT DE NEMOURS AND COMPANY (US) 2012-10-16 US disclosed
US-20110180761-A1 METHOD FOR THE APPLICATION OF ACTIVE MATERIALS ONTO A SURFACES AND DEVICES MADE WITH SUCH METHODS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-28 US disclosed
US-7686978-B2 Method for the application of active materials onto active surfaces and devices made with such methods E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-30 US disclosed
US-7686978-B2 Method for the application of active materials onto active surfaces and devices made with such methods E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-30 US disclosed
US-7531700-B2 Fluorinated arylethers and methods for use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-12 US disclosed
US-20050062021-A1 Method for the application of active materials onto active surfaces and devices made with such methods LG CHEM, LTD. (KR) 2005-03-24 US disclosed