Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554049 | 0.86 | ALDH1A1 (0.42) | GAAHTTL3MBTL1POLBLMNA | |
| SCHEMBL7253009 | 0.86 | MEN1 (0.41) | GAAHTTL3MBTL1POLBTDP1 | |
| SCHEMBL6025036 | 0.84 | GAA (0.38) | GAAHTTL3MBTL1GABRA1LMNA | |
| SCHEMBL6440225 | 0.80 | DYRK1A (0.36) | GAAHTTL3MBTL1POLBLMNA | |
| SCHEMBL6443197 | 0.79 | CNR1 (0.43) | GAAHTTMEN1KMT2A | |
| SCHEMBL2044356 | 0.77 | LMNA (0.41) | GAAHTTL3MBTL1GABRA1KDM4E | |
| SCHEMBL2563638 | 0.77 | MAPK9 (0.41) | GAAHTTL3MBTL1POLBTDP1 | |
| SCHEMBL6443205 | 0.76 | MAPK9 (0.34) | GAAHTTKDM4ELMNAMAPK9 | |
| SCHEMBL6024314 | 0.76 | MAPK9 (0.34) | GAAHTTL3MBTL1LMNAMAPK9 | |
| SCHEMBL6024760 | 0.76 | MAPK9 (0.34) | GAAHTTLMNAMAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499577-A1 | 2-(2,6-DICHLOROPHENYL)-DIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003087026-A1 | 2-(2,6-DICHLOROPHENYL)-DIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-23 | — | — | WO | disclosed |