Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024760 | 0.85 | MAPK9 (0.34) | MAPK9MAPK10GAALMNARAB9A | |
| SCHEMBL6024314 | 0.85 | MAPK9 (0.34) | MAPK9MAPK10GAAMAPTLMNA | |
| SCHEMBL6025036 | 0.85 | GAA (0.38) | MAPK9MAPK10GAALMNARAB9A | |
| SCHEMBL7253009 | 0.84 | MEN1 (0.41) | MAPK9MAPK10GAAMAPTLMNA | |
| SCHEMBL5753432 | 0.82 | PNMT (0.36) | GAALMNA | |
| SCHEMBL5745770 | 0.80 | SMN1; SMN2 (0.45) | LMNAMEN1KMT2ATSHRHTT | |
| SCHEMBL6441296 | 0.78 | ALDH1A1 (0.40) | MAPK9MAPK10GAAADRB1RAB9A | |
| SCHEMBL5746437 | 0.78 | TLR4 (0.41) | MAPTMEN1KMT2AHTR1AKDM4E | |
| SCHEMBL5764702 | 0.78 | MAPK9 (0.38) | MAPK9MAPK10GAALMNARAB9A | |
| SCHEMBL6443197 | 0.78 | CNR1 (0.43) | GAAHIF1AMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499577-A1 | 2-(2,6-DICHLOROPHENYL)-DIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003087026-A1 | 2-(2,6-DICHLOROPHENYL)-DIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-23 | — | — | WO | disclosed |