SCHEMBL64438

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31509406	1.00	MAPT (0.38)	MAPTKDM4EALOX15SMN1; SMN2MGLL
	SCHEMBL29565872	0.89	MGLL (0.40)	MAPTMGLLADRA2AADRA1ATSHR
	SCHEMBL13186139	0.88	MGLL (0.32)	MAPTKDM4EALOX15SMN1; SMN2MGLL
	SCHEMBL30917909	0.86	MGLL (0.38)	MAPTMGLLADRA2AADRA1ATSHR
	SCHEMBL28937377	0.86	MAPT (0.37)	MAPTKDM4EALOX15SMN1; SMN2ADRA2A
	SCHEMBL17452440	0.86	DNM1 (0.36)	MAPTMGLLADRA2AADRA1ATSHR
	SCHEMBL64998	0.86	DNM1 (0.36)	MAPTKDM4EALOX15SMN1; SMN2MGLL
	SCHEMBL20718939	0.84	DNM1 (0.46)	MAPTSMN1; SMN2MGLLADRA2AADRA1A
	SCHEMBL13186140	0.84	ALDH1A1 (0.39)	MAPTKDM4EALOX15SMN1; SMN2ADRA2A
	SCHEMBL889188	0.84	DNM1 (0.42)	MAPTKDM4EALOX15SMN1; SMN2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 719 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.