Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL8161423 | 0.93 | TP53 (0.41) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetone SCHEMBL5322639 | 0.90 | LMNA (0.43) | FFAR3LCKFYNTP53SLC7A5 | |
| SCHEMBL79569 | 0.89 | TP53 (0.35) | TP53SLC7A5ALDH1A1TDP1TSHR | |
| Methyl Alcohol SCHEMBL8058445 | 0.86 | TP53 (0.33) | TP53SLC7A5 | |
| Formaldehyde SCHEMBL79597 | 0.83 | SLC7A5 (0.32) | TP53SLC7A5 | |
| Isopropyl Alcohol SCHEMBL1325429 | 0.83 | ALDH1A1 (0.43) | TP53SLC7A5ALDH1A1LMNA | |
| SCHEMBL17969881 | 0.81 | TP53 (0.40) | TP53SLC7A5 | |
| Acetic Acid SCHEMBL27541991 | 0.80 | FFAR3 (0.47) | FFAR3LCKFYNTP53SLC7A5 | |
| SCHEMBL10486769 | 0.80 | ALDH1A1 (0.40) | TP53SLC7A5ALDH1A1TSHRLMNA | |
| Butanone SCHEMBL9511587 | 0.79 | ALDH1A1 (0.56) | FFAR3ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6899983-B2 | Electrophotographic photoconductor, electrophotographic apparatus and process cartridge | RICOH COMPANY, LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20040048177-A1 | Electrophotographic photoconductor, electrophotographic apparatus and process cartridge | RICOH COMPANY, LTD. (JP) | 2004-03-11 | — | — | US | disclosed |