Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446714 | 0.92 | ANPEP (0.57) | ANPEPKMT2AMEN1TSHRPSMB1 | |
| SCHEMBL6021447 | 0.89 | ANPEP (0.56) | ANPEPCTSSCTSKMAPT | |
| SCHEMBL6445458 | 0.88 | KMT2A (0.67) | ANPEPKMT2APSMB1PSMB5PSMB2 | |
| SCHEMBL6445490 | 0.85 | ANPEP (0.51) | ANPEPKMT2AMEN1TSHRPSMB1 | |
| SCHEMBL6442637 | 0.83 | KMT2A (0.61) | KMT2APSMB1PSMB5PSMB2CTSS | |
| SCHEMBL6020261 | 0.82 | CTSL (0.58) | CTSSCTSK | |
| SCHEMBL6021095 | 0.81 | CASR (0.48) | KMT2AMEN1PSMB1PSMB5PSMB2 | |
| SCHEMBL6446666 | 0.81 | CTSS (0.57) | ANPEPKMT2APSMB1PSMB5PSMB2 | |
| SCHEMBL6446628 | 0.81 | KMT2A (0.70) | ANPEPKMT2APSMB1PSMB5PSMB2 | |
| SCHEMBL6019819 | 0.81 | CASR (0.45) | CTSSCTSKNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |