Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445396 | 0.92 | ANPEP (0.54) | ANPEPKMT2AMEN1TSHRPSMB1 | |
| SCHEMBL6020101 | 0.90 | ANPEP (0.48) | ANPEPCTSSCTSKCTSBCTSL | |
| SCHEMBL6444345 | 0.85 | ANPEP (0.54) | ANPEPKMT2AMEN1TSHRPSMB1 | |
| SCHEMBL6445458 | 0.85 | KMT2A (0.67) | ANPEPKMT2APSMB1PSMB5PSMB2 | |
| SCHEMBL6021221 | 0.83 | CASR (0.45) | KMT2AMEN1PSMB1PSMB5PSMB2 | |
| SCHEMBL6019230 | 0.82 | CTSL (0.63) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6021520 | 0.82 | CTSB (0.44) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6020675 | 0.81 | CTSB (0.45) | ANPEPCTSSCTSKCTSBCTSL | |
| SCHEMBL6019506 | 0.81 | CTSS (0.53) | ANPEPCTSSCTSKCTSBCTSL | |
| SCHEMBL6442637 | 0.80 | KMT2A (0.61) | KMT2APSMB1PSMB5PSMB2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |