Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761434 | 0.95 | KDM4E (0.65) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL5012154 | 0.90 | KDM4E (0.53) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL30493949 | 0.90 | KDM4E (0.53) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL1797036 | 0.86 | KDM4E (0.53) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL5833308 | 0.83 | KDM4E (0.50) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL7992477 | 0.83 | KDM4E (0.50) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL501967 | 0.83 | KDM4E (0.50) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL1798367 | 0.83 | KDM4E (0.50) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL4854056 | 0.83 | KDM4E (0.53) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL888411 | 0.82 | KDM4E (0.56) | KDM4ESMN1; SMN2GAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563322-B | Substituted benzamide isoxazoline derivative or salt acceptable as pesticide, composition and application thereof | 海利尔药业集团股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-113563322-A | Substituted benzamide isoxazoline derivative or salt and composition thereof acceptable as pesticide and application thereof | 海利尔药业集团股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-104119268-A | Preparation and application of trifluoroacetyl anabasine compounds with insecticidal activity | UNIV JINAN | 2014-10-29 | — | — | CN | disclosed |
| CN-100389115-C | Pyridyloxymethyl and benziso * azole azabicyclic derivatives | PFIZER (US) | 2008-05-21 | — | — | CN | disclosed |
| CN-1759116-A | Pyridyloxymethyl and benzisoxazole azabicyclic derivatives | PFIZER (US) | 2006-04-12 | — | — | CN | disclosed |
| EP-1608648-A1 | PYRIDYLOXYMETHYL AND BENZISOXAZOLE AZABICYCLIC DERIVATIVES | Pfizer Products Inc. (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004081007-A1 | PYRIDYLOXYMETHYL AND BENZISOXAZOLE AZABICYCLIC DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2004-09-23 | — | — | WO | disclosed |