Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441518 | 1.00 | CTSK (0.30) | CTSK | |
| SCHEMBL4775248 | 0.86 | CTSK (0.40) | CTSK | |
| SCHEMBL4773839 | 0.86 | CTSK (0.40) | CTSK | |
| SCHEMBL14471620 | 0.85 | SELP (0.34) | CTSK | |
| SCHEMBL14471627 | 0.70 | BMP1 (0.33) | — | |
| SCHEMBL3277142 | 0.70 | CHRM1 (0.39) | CTSK | |
| SCHEMBL1901197 | 0.69 | PGD (0.30) | — | |
| SCHEMBL7434747 | 0.67 | CTSK (0.39) | CTSK | |
| SCHEMBL5183590 | 0.66 | CYP1A2 (0.36) | — | |
| SCHEMBL8133935 | 0.66 | SLC1A3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501807-A1 | SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093245-A1 | SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | WO | claimed |