Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443382 | 1.00 | EPHX1 (0.41) | EPHX1HTTALDH1A1CES2CES1 | |
| SCHEMBL6443841 | 1.00 | EPHX1 (0.41) | EPHX1HTTALDH1A1CES2CES1 | |
| SCHEMBL6441288 | 1.00 | EPHX1 (0.41) | EPHX1HTTALDH1A1CES2CES1 | |
| SCHEMBL7616017 | 0.83 | CYP3A4 (0.38) | CES2CES1KMT2A | |
| SCHEMBL4416335 | 0.79 | DNM1 (0.40) | HTTCES2CES1NAAAMEN1 | |
| SCHEMBL3813028 | 0.79 | DNM1 (0.40) | HTTCES2CES1NAAAMEN1 | |
| SCHEMBL6288242 | 0.79 | DNM1 (0.40) | HTTCES2CES1NAAAMEN1 | |
| SCHEMBL49664 | 0.79 | DNM1 (0.40) | HTTCES2CES1NAAAMEN1 | |
| SCHEMBL6288656 | 0.79 | DNM1 (0.40) | HTTCES2CES1NAAAMEN1 | |
| SCHEMBL6288219 | 0.79 | DNM1 (0.40) | HTTCES2CES1NAAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956072-B1 | Thermoplastic resin composition and molded object thereof | POLYPLASTICS CO., LTD. (JP) | 2005-10-18 | — | — | US | disclosed |