SCHEMBL4416335

SCHEMBL4416335

CCCCCCCCCCCCCCCCP(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
EPHX2 P34913 1/20 0.39
PKM P14618 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HTT P42858 2/20 0.38
KCNH2 Q12809 2/20 0.38
NAAA Q02083 1/20 0.38
PTPN11 Q06124 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
LTA4H P09960 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9561633 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL49938 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL28829104 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL647076 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL108820 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL107883 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL10871891 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6291641 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL1726443 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL10869387 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020137820-A1 Phosphorus compounds SANDOZ LTD. (CH) 2002-09-26 US claimed
US-20090318642-A1 Surface-Modified Polymerization Catalysts for the Preparation of Low-Gel Polyolefin Films BOREALIS TECHNOLOGY OY (FI) 2009-12-24 US disclosed
CN-101389667-A Surface-modified polymerization catalysts for the preparation of low-gel polyolefin films BOREALIS TECH OY (FI) 2009-03-18 CN disclosed
EP-1969019-A1 SURFACE-MODIFIED POLYMERIZATION CATALYSTS FOR THE PREPARATION OF LOW-GEL POLYOLEFIN FILMS Borealis Technology OY (FI) 2008-09-17 EP disclosed
WO-2008043388-A1 SURFACE-MODIFIED POLYMERIZATION CATALYSTS FOR THE PREPARATION OF LOW-GEL POLYOLEFIN FILMS BOREALIS TECHNOLOGY OY (FI) 2008-04-17 WO disclosed
US-7285286-B2 Antimicrobial surfaces LONG ISLAND UNIVERSITY (US) 2007-10-23 US disclosed
US-7241453-B2 Antimicrobial surfaces LONG ISLAND UNIVERSITY (US) 2007-07-10 US disclosed
EP-1803747-A1 Surface-modified polymerization catalysts for the preparation of low-gel polyolefin films Borealis Technology Oy (FI) 2007-07-04 EP disclosed
US-20060199758-A1 ANTIMICROBIAL SURFACES ENGEL ROBERT 2006-09-07 US disclosed
US-20050181006-A1 Antimicrobial surfaces PACE UNIVERSITY 2005-08-18 US disclosed
US-6864304-B2 Phosphorus compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2005-03-08 US disclosed
EP-1496823-A2 ANTIMICROBIAL SURFACES Research Foundation of the City University of New York (US) 2005-01-19 EP disclosed
WO-2003086477-A2 ANTIMICROBIAL SURFACES RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2003-10-23 WO disclosed
US-20020137820-A1 Phosphorus compounds SANDOZ LTD. (CH) 2002-09-26 US disclosed
US-6369140-B1 POLYOLEFIN AND PHOSPHINE OR PHOSPHORANE COMPOUNDS STABILIZERS; OXIDATION, HEAT, STRESS, AND ULTRAVIOLET RADIATION RESISTANCE CLARIANT FINANCE (BVI) LIMITED (BV) 2002-04-09 US disclosed
US-5488079-A HEAT AND LIGHT STABILIZERS FOR OLEFINS USING PHOSPHINES SANDOZ LTD. (CH) 1996-01-30 US disclosed
EP-0495803-B1 DISINFECTANT COMPOSITION AND METHOD OF DISINFECTION FABRICOM AIR CONDITIONING SA (BE) 1995-05-10 EP disclosed
WO-1991004668-A1 DISINFECTANT COMPOSITION AND METHOD OF DISINFECTION FABRICOM AIR CONDITIONING S.A. (BE) 1991-04-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060199758-A1 ANTIMICROBIAL SURFACES TLR2, NR0B2, FPR2 DNM1 685/4885MEN1 4287/4885KMT2A 2824/4885
US-20050181006-A1 Antimicrobial surfaces QSOX1, LBR, FPR1 DNM1 65/4885MEN1 3826/4885KMT2A 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.