SCHEMBL6445504

SCHEMBL6445504

CC=C1C(=O)OC(=O)C1C=Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
LMNA P02545 4/20 0.41
KDM4E B2RXH2 3/20 0.41
HTT P42858 2/20 0.41
POLB P06746 1/20 0.41
ADORA3 P0DMS8 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
XBP1 P17861 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
JAK2 O60674 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
KDM1A O60341 3/20 0.37
MAOA P21397 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27471426 0.77 LMNA (0.40) MAPTLMNAKDM4EHTTPOLB
SCHEMBL28808239 0.72 MEN1 (0.40) MAPTLMNAKDM4EHTTPOLB
SCHEMBL29808265 0.72 MEN1 (0.40) MAPTLMNAKDM4EHTTPOLB
SCHEMBL29810734 0.72 MEN1 (0.40) MAPTLMNAKDM4EHTTPOLB
SCHEMBL27719239 0.69 GAA (0.45) MAPTLMNAKDM4EPOLBMEN1
SCHEMBL8859198 0.66 KDM1A (0.47) MAPTLMNAKDM4EHTTPOLB
SCHEMBL10867130 0.66 LMNA (0.46) MAPTLMNAHTTMEN1KMT2A
SCHEMBL13075286 0.63 KDM1A (0.53) MAPTLMNAHTTMEN1KMT2A
SCHEMBL7126327 0.63 LMNA (0.40) MAPTLMNAKDM4EHTTMEN1
SCHEMBL13346970 0.63 KDM1A (0.53) MAPTLMNAHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1146083-B1 USE OF A RESIN MATERIAL FOR ELECTRICAL INSULATING AND ELECTRIC WIRE AND CABLE USING THE SAME JAPAN POLYOLEFINS CO LTD (JP) 2005-01-05 EP disclosed
EP-0674325-B1 Electrically insulating polymer composition and wire or cable using the same NIPPON PETROCHEMICALS CO LTD (JP) 2003-11-05 EP disclosed
US-6479590-B1 Electrical insulating resin material, electrical insulating material, and electric wire and cable using the same JAPAN POLYOLEFINS CO., LTD. (JP) 2002-11-12 US disclosed
EP-1146083-A1 ELECTRICAL INSULATING RESIN MATERIAL, ELECTRICAL INSULATING MATERIAL, AND ELECTRIC WIRE AND CABLE USING THE SAME Japan Polyolefins Co., Ltd. (JP) 2001-10-17 EP disclosed
EP-0674325-A2 Electrically insulating polymer composition and wire or cable using the same Nippon Petrochemicals Co., Ltd. (JP) 1995-09-27 EP disclosed