Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29810734 | 1.00 | MEN1 (0.40) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL29808265 | 1.00 | MEN1 (0.40) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL7455751 | 0.77 | MAOA (0.42) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL28949966 | 0.73 | ALDH1A1 (0.51) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL6445504 | 0.72 | MAPT (0.41) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL8859198 | 0.67 | KDM1A (0.47) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL20785352 | 0.66 | MAOA (0.46) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL20169271 | 0.66 | MAOA (0.46) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL20785351 | 0.66 | MAOA (0.46) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL20785354 | 0.66 | MAOA (0.46) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835665-A | Novel cis-styryl benzofuranone compound and efficient synthesis method thereof | 湖南大学 | 2022-08-02 | — | — | CN | claimed |
| CN-114835665-A | Novel cis-styryl benzofuranone compound and efficient synthesis method thereof | 湖南大学 | 2022-08-02 | — | — | CN | disclosed |