SCHEMBL6445532

SCHEMBL6445532

CCCCCCCCCCCCP(C)(=O)O

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 3/20 0.68
LPAR2 Q9HBW0 1/20 0.68
GABBR2 O75899 1/20 0.54
CYP1A2 P05177 1/20 0.54
TSHR P16473 1/20 0.54
THPO P40225 1/20 0.54
GABBR1 Q9UBS5 1/20 0.54
LMNA P02545 1/20 0.52
BLM P54132 1/20 0.52
TRPM8 Q7Z2W7 4/20 0.50
S1PR1 P21453 7/20 0.49
S1PR3 Q99500 7/20 0.49
S1PR2 O95136 6/20 0.49
S1PR4 O95977 6/20 0.49
S1PR5 Q9H228 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440917 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL600687 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL9876090 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL6445380 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL6440597 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL6441961 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL3820923 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL6448034 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL5606003 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR
SCHEMBL9875102 1.00 LPAR3 (0.68) LPAR3LPAR2GABBR2CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140255459-A1 METHOD OF SURFACE TREATMENT OF MICRO/NANOPARTICLES BY CHEMICAL MEANS AND ITS APPLICATION TO OBTAINING A PIGMENT COMPOSITION INTENDED FOR THE FIELD OF COSMETICS, PAINT OR INKS SIKEMIA (FR) 2014-09-11 US disclosed
US-20070140973-A1 CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING BRISTOL-MYERS SQUIBB PHARMA COMPANY 2007-06-21 US disclosed
US-6956072-B1 Thermoplastic resin composition and molded object thereof POLYPLASTICS CO., LTD. (JP) 2005-10-18 US disclosed
US-4983566-A Surface-modified adsorbent comprising metal oxide/hydroxide particles reacted with one or more perfluorinated organic acids ALUMINUM COMPANY OF AMERICA (US) 1991-01-08 US disclosed
US-4250124-A FIREPROOFING TEXTILES; REACTION OF AN HYDROXY-CONTAINING COMPOUND AND A 2-SUBSTITUTED-2-OXO-OXA-PHOSPHOLANE HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4244893-A FIREPROOFING; FINISHES FOR TEXTILES HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-13 US disclosed
EP-0019187-A2 Organic phosphorus compounds with 3-hydroxyalkyl-phosphonic acid ester groups, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-26 EP disclosed
US-4220610-A Organic phosphorus compounds with 2-hydroxyalkyl-phosphonic acid groups HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-02 US disclosed
EP-0009706-A1 Organic phosphorus compounds containing 3-hydroxyalkylphosphinic acid ester groups, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1980-04-16 EP disclosed
EP-0003599-A1 Organic phosphorus compounds with 2-hydroxyalkylphosphoric acid groups, process for their preparation and their use as flame retardants HOECHST AKTIENGESELLSCHAFT (DE) 1979-08-22 EP disclosed
US-4163034-A DECYCLIZATION, ESTERIFICATION; FIREPROOFING HOECHST AG. (DE) 1979-07-31 US disclosed
EP-0002733-A2 Method of preparing phosphinic or phosphonic acid anhydrides HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 EP disclosed
US-4138433-A Process for preparing 1,2-oxa-phospholanes HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
EP-0000024-A1 Polyadducts containing phosphorus and their application in the flameproofing of textile materials HOECHST AKTIENGESELLSCHAFT (DE) 1978-12-20 EP disclosed
US-4096208-A FIREPROOFING AGENTS HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140255459-A1 METHOD OF SURFACE TREATMENT OF MICRO/NANOPARTICLES BY CHEMICAL MEANS AND ITS APPLICATION TO OBTAINING A PIGMENT COMPOSITION INTENDED FOR THE FIELD OF COSMETICS, PAINT OR INKS TYR, MITF, MC1R LPAR3 2735/4885LPAR2 3457/4885GABBR2 2932/4885
US-20070140973-A1 CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING TNNI3, TNNT2, TNNC1 LPAR3 567/4885LPAR2 1562/4885GABBR2 4704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.