Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.55 |
| ▸ | CTSS | P25774 | 12/20 | 0.55 |
| ▸ | CTSL | P07711 | 10/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442367 | 0.90 | CTSK (0.50) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6443547 | 0.88 | CTSK (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6447319 | 0.87 | CTSK (0.48) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6822579 | 0.85 | CTSK (0.54) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5526073 | 0.84 | CTSK (0.62) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5517758 | 0.81 | CTSK (0.61) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6442556 | 0.81 | CTSS (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6443108 | 0.79 | CTSS (0.48) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6444143 | 0.79 | CTSK (0.45) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6443377 | 0.78 | CTSK (0.55) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | claimed |
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |