Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468074 | 0.79 | KDM4E (0.50) | MRGPRX4CA2CA12 | |
| SCHEMBL3800027 | 0.79 | CA2 (0.49) | LTA4HMRGPRX4CA2CA12 | |
| SCHEMBL828208 | 0.79 | CA2 (0.49) | LTA4HMRGPRX4CA2CA12 | |
| SCHEMBL3809957 | 0.77 | SIGMAR1 (0.56) | LTA4HMRGPRX4CA2CA12 | |
| Hydrochloric Acid SCHEMBL3815309 | 0.76 | SIGMAR1 (0.55) | LTA4HMRGPRX4CA2CA12 | |
| SCHEMBL2988516 | 0.75 | MRGPRX4 (0.47) | MRGPRX4CA2CA12 | |
| SCHEMBL5564792 | 0.75 | MRGPRX4 (0.50) | MRGPRX4CA2CA12 | |
| SCHEMBL3793751 | 0.75 | CA2 (0.51) | MRGPRX4CA2CA12 | |
| SCHEMBL3164463 | 0.75 | NR5A1 (0.47) | LTA4HMRGPRX4CA2CA12 | |
| SCHEMBL5566031 | 0.74 | TBXAS1 (0.54) | LTA4HESR1ESR2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594857-A2 | N-MONOACYLATED O-PHENYLENEDIAMINES AS ANTI-CANCER AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004069133-A2 | N-MONOACYLATED O-PHENYLENEDIAMINES AS ANTI -CANCER AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-19 | — | — | WO | disclosed |