Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.36 |
| ▸ | FASN | P49327 | 2/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.35 |
| ▸ | PDE1A | P54750 | 3/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429703 | 0.91 | PDGFRB (0.36) | HPGDSPDE1BPDE1CPDE1ALRRK2 | |
| SCHEMBL5845474 | 0.75 | HPGDS (0.38) | HPGDSCYP3A4HPGDPDE1BFASN | |
| SCHEMBL6465311 | 0.74 | HPGD (0.39) | CYP3A4HPGDNPC1RAB9A | |
| SCHEMBL6795536 | 0.70 | PDE1B (0.37) | HPGDSPDE1BPDE1CPDE1ADGAT2 | |
| SCHEMBL6797756 | 0.69 | HPGDS (0.35) | HPGDSPDE1BLRRK2 | |
| SCHEMBL6800033 | 0.69 | GRM5 (0.38) | HPGDSPDE1B | |
| SCHEMBL6429820 | 0.67 | KDM4E (0.34) | CYP3A4HPGD | |
| SCHEMBL6797091 | 0.67 | MCHR1 (0.35) | HPGDSPDE1BPDE1CPDE1A | |
| SCHEMBL6797534 | 0.65 | PDE1B (0.36) | HPGDSPDE1BPDE1CPDE1ALRRK2 | |
| SCHEMBL5844055 | 0.65 | PDE1B (0.36) | HPGDSPDE1BPDE1CPDE1ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891005-B2 | Bridged metal complexes for gas phase polymerizations | BP CHEMICALS LIMITED (GB) | 2005-05-10 | — | — | US | disclosed |
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |
| US-20030199650-A1 | Bridged metal complexes for gas phase polymerizations | BP CHEMICALS LIMITED | 2003-10-23 | — | — | US | disclosed |
| EP-1119575-B1 | BRIDGED METAL COMPLEXES | DOW CHEMICAL CO (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-1141034-B1 | BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS | BP CHEM INT LTD (GB) | 2002-10-30 | — | — | EP | disclosed |
| US-6376406-B1 | COORDINATION POLYMERIZATION CATALYSTS FOR ALPHA-OLEFINS | THE DOW CHEMICAL COMPANY | 2002-04-23 | — | — | US | disclosed |
| US-6284905-B1 | GROUP 4 TRANSITION METAL COMPLEX CONTAINING A BORON OR ALUMINUM BRIDGING GROUP CONTAINING A NITROGEN CONTAINING ELECTRON DONATING GROUP, ESPECIALLY AN AMIDO GROUP; OLEFIN SOLUTION OR SLURRY POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY | 2001-09-04 | — | — | US | disclosed |
| EP-1119575-A1 | BRIDGED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020426-A1 | BRIDGED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |