Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | LIPA | P38571 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446930 | 1.00 | LMNA (0.41) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6443859 | 0.96 | LMNA (0.39) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6442202 | 0.96 | LMNA (0.39) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6445468 | 0.93 | KMT2A (0.39) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6444372 | 0.93 | KMT2A (0.39) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6445873 | 0.90 | LMNA (0.40) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6445456 | 0.90 | LMNA (0.42) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6442138 | 0.90 | LMNA (0.40) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6443811 | 0.90 | LMNA (0.42) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6439906 | 0.89 | CYP3A4 (0.40) | LMNAMAPTKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050159366-A1 | Pharmaceutical compositions and treatment methods - 8 | BIOVIE INC. | 2005-07-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159366-A1 | Pharmaceutical compositions and treatment methods - 8 | HSD17B7, NR5A1, HSD3B1 | LMNA 4071/4885MAPT 2579/4885KMT2A 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.