Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445669 | 1.00 | ESR1 (0.41) | ESR1ESR2NPC1RAB9ANPSR1 | |
| SCHEMBL6451505 | 0.84 | TRPA1 (0.41) | FAAHTRPV1KMT2AMAOB | |
| SCHEMBL6449983 | 0.84 | LMNA (0.42) | ESR1ESR2RAB9AALDH1A1CYP3A4 | |
| SCHEMBL6445781 | 0.84 | KMT2A (0.43) | NPC1RAB9ANPSR1FAAHTRPV1 | |
| SCHEMBL6449984 | 0.84 | LMNA (0.42) | ESR1ESR2RAB9AALDH1A1CYP3A4 | |
| SCHEMBL6451511 | 0.84 | TRPA1 (0.41) | FAAHTRPV1KMT2AMAOB | |
| SCHEMBL6445784 | 0.84 | KMT2A (0.43) | NPC1RAB9ANPSR1FAAHTRPV1 | |
| SCHEMBL6450150 | 0.83 | KMT2A (0.38) | FAAHKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6450146 | 0.83 | KMT2A (0.38) | FAAHKMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6450387 | 0.83 | L3MBTL1 (0.42) | NPC1RAB9AFAAHTRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921832-B2 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2005-07-26 | — | — | US | disclosed |
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1422226-A1 | Optically active fluorine-containing compounds and processes for their production | Tosoh Corporation (JP) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | CYP2C19, CYP2F1, CYP2B6 | ESR1 1207/4885ESR2 309/4885NPC1 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.