SCHEMBL6445686

SCHEMBL6445686

CCCCCCCCCCCC[SiH2]c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
EPHX2 P34913 1/20 0.39
PKM P14618 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HTT P42858 2/20 0.38
KCNH2 Q12809 2/20 0.38
NAAA Q02083 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
LTA4H P09960 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31216177 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6446347 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL9665893 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6443323 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6443439 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL3678757 0.98 LTA4H (0.38) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL27860425 0.96 DNM1 (0.38) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL1274186 0.91 LTA4H (0.38) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL27968744 0.91 HTR2A (0.38) DNM1MEN1KMT2ATP53MAPK1
Fluoride SCHEMBL27639867 0.89 LTA4H (0.36) DNM1MEN1KMT2ATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101429257-B Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and manufacturing method of addition polymer SUMITOMO CHEMICAL CO 2011-02-02 CN disclosed
CN-101429257-A Modified particle and its manufacturing method, carrier, catalyst component for addition polymerization, catalyst for addition polymerization and manufacturing method of addition polymer SUMITOMO CHEMICAL CO (JP) 2009-05-13 CN disclosed
CN-100482695-C Modified particle, method for producing catalyst component or catalyst for addition polymerization, and method for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2009-04-29 CN disclosed
CN-101157707-A Metallic compound, catalytic component for addition polymerization, catalyst for addition polymerization and method for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2008-04-09 CN disclosed
CN-1693314-A Modified particle, method for producing catalyst component or catalyst for addition polymerization, and method for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2005-11-09 CN disclosed
US-6858164-B2 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2005-02-22 US disclosed
CN-1517368-A Metal compound, catalyst component and catalyst for addition polymerization, and process for producing addition polymer ס�ѻ�ѧ��ҵ��ʽ���� 2004-08-04 CN disclosed