SCHEMBL6446347

SCHEMBL6446347

CCCCCC[SiH2]c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
EPHX2 P34913 1/20 0.39
PKM P14618 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HTT P42858 2/20 0.38
KCNH2 Q12809 2/20 0.38
NAAA Q02083 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
LTA4H P09960 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31216177 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL9665893 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6443323 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6443439 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6445686 1.00 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL3678757 0.98 LTA4H (0.38) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL27860425 0.96 DNM1 (0.38) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL1274186 0.91 LTA4H (0.38) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL27968744 0.91 HTR2A (0.38) DNM1MEN1KMT2ATP53MAPK1
Fluoride SCHEMBL27639867 0.89 LTA4H (0.36) DNM1MEN1KMT2ATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120142517-A Method for identifying formula particles and various types of cynanchum atratum and application 北京康仁堂药业有限公司 2025-06-13 CN claimed
CN-119198997-A Collagenase detection method 远大生命科学(鞍山)有限公司 2024-12-27 CN claimed
CN-117451894-A Separation detection method for roxatidine acetate or salt and impurities thereof 四川汇宇制药股份有限公司 2024-01-26 CN claimed
CN-113960234-B Quality control method for cynanchum glaucescens and cynanchum glaucescens formula granules 北京康仁堂药业有限公司 2023-04-07 CN claimed
CN-113960234-A Quality control method for cynanchum glaucescens and cynanchum glaucescens formula granules 北京康仁堂药业有限公司 2022-01-21 CN claimed
CN-109187825-B Method for measuring content of radix trichosanthis or medicine prepared by taking radix trichosanthis as raw material 四川新绿色药业科技发展有限公司 2021-09-28 CN claimed
CN-109187825-A A kind of radices trichosanthis or the content assaying method containing the drug that radices trichosanthis is raw material preparation 四川新绿色药业科技发展有限公司 2019-01-11 CN claimed
US-20010054579-A1 METHOD OF SEPARATING DIFFERENT CHEMICALS IN A SAMPLE AHMED FAIZY (US) 2001-12-27 US claimed
CN-122109387-A Method for detecting nitrosamine impurities in terbinafine hydrochloride spray 2026-05-29 CN disclosed
CN-120142517-A Method for identifying formula particles and various types of cynanchum atratum and application 北京康仁堂药业有限公司 2025-06-13 CN disclosed
CN-119198997-A Collagenase detection method 远大生命科学(鞍山)有限公司 2024-12-27 CN disclosed
WO-2024247753-A1 BISSILYL COMPOUND HAVING SILYL GROUP SUBSTITUTED WITH ORGANOXYSILYLALKYLAMINO GROUP AND METHOD FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT CONTAINING SAME 信越化学工業株式会社 2024-12-05 WO disclosed
CN-118852230-A Preparation method of polysubstituted hydrosilane compound 中国科学院兰州化学物理研究所 2024-10-29 CN disclosed
CN-117451894-A Separation detection method for roxatidine acetate or salt and impurities thereof 四川汇宇制药股份有限公司 2024-01-26 CN disclosed
CN-102282212-A Polycarbonate resin composition and molded article thereof 2011-12-14 CN disclosed
CN-101596155-A Teniposide solid lipid nanoparticle and preparation method thereof SHANGHAI INST MATERIA MEDICA (CN) 2009-12-09 CN disclosed
CN-101579312-A Teniposide liposome and preparation method thereof SHANGHAI INST MATERIA MEDICA (CN) 2009-11-18 CN disclosed
US-6858164-B2 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2005-02-22 US disclosed
US-5866306-A POLYALKYLPHENYLSILANE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-02-02 US disclosed
EP-0502662-A1 Process for use of photosensitive polysilanes as a photoresist International Business Machines Corporation (US) 1992-09-09 EP disclosed