SCHEMBL6445704

SCHEMBL6445704

CCCCOC(=O)C12C=CC(CC1)C2.COC(=O)C12C=CC(CC1)C2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
RAB9A P51151 4/20 0.32
HSD17B10 Q99714 1/20 0.32
EPHX2 P34913 4/20 0.31
ATM Q13315 1/20 0.31
LMNA P02545 2/20 0.31
TSHR P16473 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NPC1 O15118 3/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
MAPT P10636 2/20 0.31
CASP1 P29466 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
MCL1 Q07820 1/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2350192 0.95 ALDH1A1 (0.36) ALDH1A1RAB9AHSD17B10EPHX2ATM
SCHEMBL4336336 0.90 MEN1 (0.33) ALDH1A1ATMLMNATSHRL3MBTL1
SCHEMBL10595092 0.90 NAAA (0.38) ALDH1A1RAB9AEPHX2LMNATSHR
SCHEMBL10591972 0.90 NAAA (0.38) ALDH1A1RAB9AEPHX2LMNATSHR
SCHEMBL10595248 0.90 NAAA (0.38) ALDH1A1RAB9AEPHX2LMNATSHR
SCHEMBL28550237 0.90 NAAA (0.38) ALDH1A1RAB9AEPHX2LMNATSHR
SCHEMBL10592103 0.90 NAAA (0.38) ALDH1A1RAB9AEPHX2LMNATSHR
SCHEMBL1451329 0.86 PPM1B (0.31) ALDH1A1HSD17B10LMNATSHRNPSR1
SCHEMBL996861 0.85 NPSR1 (0.32) NPSR1MAPT
SCHEMBL4343109 0.82 POLA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1563001-B1 NEGATIVE C-PLATE TYPE OPTICAL ANISOTROPIC FILM COMPRISING POLY CYCLOOLEFIN AND METHOD FOR PREPARING THE SAME LG CHEMICAL LTD (KR) 2017-11-01 EP disclosed
CN-101149447-A Unified polarizing plate and method for preparing the same LG CHEMICAL LTD (KR) 2008-03-26 CN disclosed
EP-1563001-A2 NEGATIVE C-PLATE TYPE OPTICAL ANISOTROPIC FILM COMPRISING POLY CYCLOOLEFIN AND METHOD FOR PREPARING THE SAME LG Chem, Ltd. (KR) 2005-08-17 EP disclosed
WO-2004049011-A2 NEGATIVE C-PLATE TYPE OPTICAL ANISOTROPIC FILM COMPRISING POLY CYCLOOLEFIN AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2004-06-10 WO disclosed