SCHEMBL996861

SCHEMBL996861

COC(=O)C12C=CC(CC1)C2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.32
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31178055 1.00 NPSR1 (0.32) NPSR1MAPTMEN1CYP3A4KMT2A
SCHEMBL7157746 0.94
SCHEMBL949926 0.85
SCHEMBL6445704 0.85 ALDH1A1 (0.33) NPSR1MAPT
SCHEMBL28646351 0.83
SCHEMBL4343109 0.83 POLA1 (0.31)
SCHEMBL7130935 0.82
SCHEMBL4247811 0.81 OPRM1 (0.33) MEN1CYP3A4KMT2A
SCHEMBL511963 0.81
SCHEMBL5918210 0.81 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806572-B Synthesis method and application of amino nickel imine complex 郑州大学 2024-11-26 CN claimed
CN-118515714-A Ortho-fluorine-containing alpha-diimine nickel complex and synthetic method and application thereof 郑州大学 2024-08-20 CN claimed
CN-117659100-A Amido imine nickel catalyst containing oxa ligand group, synthetic method and application thereof 郑州大学 2024-03-08 CN claimed
CN-116948068-A Preparation method and application of hyperbranched polyethylene 浙江巨化技术中心有限公司 2023-10-27 CN claimed
CN-115806572-A Synthesis method and application of amino imine nickel complex 郑州大学 2023-03-17 CN claimed
CN-112745431-A Cycloolefin copolymer and preparation method thereof 广东新华粤石化集团股份公司 2021-05-04 CN claimed
US-10625493-B2 Sealant film and laminate film DIC CORPORATION (JP) 2020-04-21 US claimed
EP-0856024-B1 POLYMERISABLE COMPOSITION AND POLYMERISATION METHOD CIBA SC HOLDING AG (CH) 2003-11-19 EP claimed
US-4994535-A Molding material HERCULES INCORPORATED (US) 1991-02-19 US claimed
EP-0283719-A2 Metathesis polymerized cross-linked halogen-containing copolymer HERCULES INCORPORATED (US) 1988-09-28 EP claimed
US-12612487-B2 Cycloolefin copolymer and hydrogenated product thereof, and optical element ZEON CORPORATION (JP) 2026-04-28 US disclosed
US-20260035153-A1 FRANGIBLE FILM AND PACKAGING MATERIAL DIC CORPORATION (JP) 2026-02-05 US disclosed
EP-4566816-A1 FRANGIBLE FILM AND PACKAGING MATERIAL DIC Corporation (JP) 2025-06-11 EP disclosed
US-20250179232-A1 RESIN COMPOSITION, MOLDED PRODUCT, AND OPTICAL MEMBER ZEON CORPORATION (JP) 2025-06-05 US disclosed
US-12308523-B2 Radio wave absorbing composition and radio wave absorber FUJIFILM CORPORATION (JP) 2025-05-20 US disclosed
EP-0374903-A2 Process for producing flame-retarded polymer molded articles HERCULES INCORPORATED (US) 1990-06-27 EP disclosed
EP-0305933-A2 Process for producing a molded article of metathesis polymerized polymer HERCULES INCORPORATED (US) 1989-03-08 EP disclosed
EP-0283719-A2 Metathesis polymerized cross-linked halogen-containing copolymer HERCULES INCORPORATED (US) 1988-09-28 EP disclosed
US-4205020-A USED FOR MACHINE CASINGS, PIPES, CRASH HELMETS AND TELEPHONES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-05-27 US disclosed
US-4151224-A DIENE RUBBER, ACRYLONITRILE, AROMATIC OLEFIN WITH A MINOR AMOUNT OF MALEIMIDE OR NORBORNENE OR THEIR DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035153-A1 FRANGIBLE FILM AND PACKAGING MATERIAL MALT1, PTPRA, PTPRF NPSR1 3901/4885MAPT 369/4885MEN1 3373/4885
US-12612487-B2 Cycloolefin copolymer and hydrogenated product thereof, and optical element HSF1, MALT1, HSPA4L NPSR1 1178/4885MAPT 1370/4885MEN1 2700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.