Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844565 | 0.85 | CRHR1 (0.39) | S1PR4CRHR1DCTPP1 | |
| SCHEMBL6445853 | 0.80 | S1PR4 (0.32) | S1PR4CRHR1DCTPP1L3MBTL1 | |
| SCHEMBL5844211 | 0.72 | CRHR1 (0.38) | S1PR4CRHR1 | |
| SCHEMBL5845747 | 0.71 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5843244 | 0.70 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL5842960 | 0.70 | CRHR1 (0.38) | CRHR1L3MBTL1 | |
| SCHEMBL6428567 | 0.70 | CRHR1 (0.39) | S1PR4CRHR1 | |
| SCHEMBL5844044 | 0.68 | CRHR1 (0.57) | CRHR1 | |
| Hydrochloric Acid SCHEMBL7624857 | 0.68 | POLB (0.33) | S1PR4L3MBTL1 | |
| SCHEMBL5843144 | 0.66 | CRHR1 (0.69) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |