Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844565 | 0.80 | CRHR1 (0.39) | S1PR4KDM4EMAPTMAPK1TDP1 | |
| SCHEMBL6445851 | 0.80 | S1PR4 (0.32) | S1PR4DCTPP1L3MBTL1CRHR1 | |
| SCHEMBL5842960 | 0.67 | CRHR1 (0.38) | KDM4EMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL5844211 | 0.67 | CRHR1 (0.38) | S1PR4MAPTMAPK1CRHR1 | |
| SCHEMBL5845747 | 0.66 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5843244 | 0.66 | CRHR1 (0.42) | KDM4EMAPTMAPK1TDP1CRHR1 | |
| SCHEMBL6428567 | 0.63 | CRHR1 (0.39) | S1PR4MAPTCRHR1 | |
| SCHEMBL5844044 | 0.63 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL18031283 | 0.61 | ALDH1A1 (0.44) | S1PR4KDM4EMAPTTDP1DCTPP1 | |
| SCHEMBL5843013 | 0.60 | CRHR1 (0.50) | MAPTPOLBCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |