Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK39 | Q9UEW8 | 5/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.50 |
| ▸ | PARG | Q86W56 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451577 | 0.94 | STK39 (0.62) | STK39PARGCTSDPNLIPMEN1 | |
| SCHEMBL6451555 | 0.91 | CSNK2A2 (0.55) | CSNK2A2CSNK2A1MEN1NPC1RAB9A | |
| SCHEMBL6448237 | 0.90 | STK39 (0.49) | STK39CSNK2A2CSNK2A1PARGCTSD | |
| SCHEMBL6445760 | 0.88 | CSNK2A2 (0.52) | STK39CSNK2A2CSNK2A1MEN1NPC1 | |
| SCHEMBL6447053 | 0.88 | CSNK2A2 (0.49) | STK39CSNK2A2CSNK2A1CTSDMEN1 | |
| SCHEMBL6447202 | 0.88 | KMT2A (0.46) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6445978 | 0.87 | SNCA (0.47) | STK39CSNK2A2CSNK2A1MEN1NPC1 | |
| SCHEMBL6453685 | 0.85 | MAPT (0.54) | CTSDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL6449238 | 0.85 | CSNK2A2 (0.52) | STK39CSNK2A2CSNK2A1MEN1NPC1 | |
| SCHEMBL6445643 | 0.85 | CSNK2A2 (0.46) | STK39CSNK2A2CSNK2A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143384-A1 | Amide thiadiazole inhibitors of plasminogen activator inhibitor-1 | BRISTOL-MYERS SQUIBB COMPANY | 2005-06-30 | — | — | US | claimed |
| US-20050143384-A1 | Amide thiadiazole inhibitors of plasminogen activator inhibitor-1 | BRISTOL-MYERS SQUIBB COMPANY | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143384-A1 | Amide thiadiazole inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | STK39 1010/4885CSNK2A2 2523/4885CSNK2A1 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.