⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125839 | 0.84 | ADRB2 (0.36) | — | |
| SCHEMBL7760552 | 0.81 | — | — | |
| SCHEMBL4168325 | 0.80 | CA1 (0.31) | — | |
| SCHEMBL15194655 | 0.79 | — | — | |
| SCHEMBL7763472 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL329896 | 0.77 | — | — | |
| SCHEMBL3194552 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL3483952 | 0.74 | — | — | |
| SCHEMBL3483954 | 0.74 | — | — | |
| SCHEMBL106941 | 0.72 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914364-A | MIXING DIENE ELASTOMER, AN ALKYLALKOXYSILANE, PRECIPITATED SILICA, CARBON BLACK AND A SILICA COUPLER (ESPECIALLY BIS(TRIALKOXYSILYLALKYL)POLYSULFIDE IS THE ABSENCE OF SULFUR OR A DONOR. | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-06-22 | — | — | US | claimed |
| EP-0864605-A2 | Silica reinforced rubber composition and tire with tread | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-09-16 | — | — | EP | claimed |
| US-5344905-A | Diorganopolysiloxane and method for the preparation thereof | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| EP-2097483-B1 | CURABLE SILICONE COMPOSITION | DOW CORNING TORAY SILICONE (JP) | 2014-08-20 | — | — | EP | disclosed |
| US-8802506-B2 | Method of manufacturing a semiconductor device and a semiconductor device produced thereby | DOW CORNING TORAY COMPANY, LTD. (JP) | 2014-08-12 | — | — | US | disclosed |
| EP-2197954-B1 | CURABLE LIQUID EPOXY RESIN COMPOSITION AND CURED PRODUCT THEREOF | DOW CORNING TORAY CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-8338527-B2 | Curable silicone composition and electronic components | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-2066734-B1 | DIORGANOPOLYSILOXANE AND METHOD OF MANUFACTURING THEREOF | DOW CORNING TORAY CO LTD (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-8273815-B2 | Curable silicone composition and electronic component | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-8119744-B2 | Curable silicone composition | DOW CORNING TORAY CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-7994246-B2 | Curable silicone composition and electronic component | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| EP-1086174-A1 | POWDERY MODIFIED LOADING MATERIAL CONTAINING RUBBER POWDER, METHOD FOR THE PRODUCTION AND USE THEREOF | PKU Pulverkautschuk Union GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999054397-A1 | POWDERY MODIFIED LOADING MATERIAL CONTAINING RUBBER POWDER, METHOD FOR THE PRODUCTION AND USE THEREOF | PKU PULVERKAUTSCHUK UNION GMBH (DE) | 1999-10-28 | — | — | WO | disclosed |
| US-5914364-A | MIXING DIENE ELASTOMER, AN ALKYLALKOXYSILANE, PRECIPITATED SILICA, CARBON BLACK AND A SILICA COUPLER (ESPECIALLY BIS(TRIALKOXYSILYLALKYL)POLYSULFIDE IS THE ABSENCE OF SULFUR OR A DONOR. | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0864605-A2 | Silica reinforced rubber composition and tire with tread | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5596116-A | Process for the preparation of silane polysulfides | OSI SPECIALTIES, INC. (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0705838-A2 | Process for the preparation of silane polysulfides | OSi SPECIALTIES, INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5489701-A | REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION | OSI SPECIALTIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5466848-A | Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane | OSI SPECIALTIES, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5344905-A | Diorganopolysiloxane and method for the preparation thereof | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |