SCHEMBL7763472

SCHEMBL7763472

CCCC[CH][Si](OCCC)(OCCC)OCCC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760552 0.85
SCHEMBL2361815 0.83 TSHR (0.36) TSHRALDH1A1
SCHEMBL7764826 0.81 ADRB2 (0.35) TSHRALDH1A1
SCHEMBL930993 0.77 LPAR3 (0.35) TSHRALDH1A1
SCHEMBL17633935 0.77 LPAR3 (0.35) TSHRALDH1A1
SCHEMBL644644 0.77
SCHEMBL2361158 0.76 TSHR (0.37) TSHRALDH1A1
SCHEMBL2361174 0.75 TSHR (0.38) TSHRALDH1A1
SCHEMBL9312908 0.74 TSHR (0.41) TSHR
SCHEMBL3761507 0.74 TSHR (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705838-B1 Process for the preparation of silane polysulfides CROMPTON CORP (US) 2001-05-23 EP disclosed
US-5596116-A Process for the preparation of silane polysulfides OSI SPECIALTIES, INC. (US) 1997-01-21 US disclosed
EP-0705838-A2 Process for the preparation of silane polysulfides OSi SPECIALTIES, INC. (US) 1996-04-10 EP disclosed
US-5489701-A REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION OSI SPECIALTIES, INC. (US) 1996-02-06 US disclosed
US-5466848-A Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane OSI SPECIALTIES, INC. (US) 1995-11-14 US disclosed