Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.30 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445253 | 0.94 | TP53 (0.39) | TP53TDP1LPLLIPGDRD2 | |
| SCHEMBL30540423 | 0.78 | TP53 (0.47) | TP53TDP1HDAC4MEF2DLPL | |
| SCHEMBL489025 | 0.78 | TP53 (0.47) | TP53TDP1HDAC4MEF2DLPL | |
| SCHEMBL5036861 | 0.77 | LPL (0.51) | TP53TDP1LPLLIPG | |
| SCHEMBL8759179 | 0.76 | CA1 (0.36) | TP53ALDH1A1TSHR | |
| SCHEMBL6785971 | 0.76 | TAAR1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL1396277 | 0.76 | TAAR1 (0.46) | ALDH1A1DRD2 | |
| SCHEMBL28123652 | 0.76 | CYP1A2 (0.50) | TDP1 | |
| SCHEMBL488957 | 0.76 | LPL (0.53) | TP53TDP1LPLLIPG | |
| SCHEMBL8519552 | 0.76 | LPL (0.53) | TP53TDP1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506319-A | LOW HYSTERESIS LOW, ABRASION RESISTANCE, WET SKID RESISTANCE | BRIDGESTONE CORPORATION (JP) | 1996-04-09 | — | — | US | claimed |
| JP-6263775-A | — | — | None | — | — | JP | disclosed |
| EP-1184412-B1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | BRIDGESTONE CORP (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6822027-B2 | MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. | BRIDGESTONE CORPORATION (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20020049294-A1 | Rubber composition and heavy duty pneumatic tire using the rubber composition | BRIDGESTONE CORPORATION | 2002-04-25 | — | — | US | disclosed |
| EP-1184412-A1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | Bridgestone Corporation (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5506319-A | LOW HYSTERESIS LOW, ABRASION RESISTANCE, WET SKID RESISTANCE | BRIDGESTONE CORPORATION (JP) | 1996-04-09 | — | — | US | disclosed |
| JP-H06263775-A | VINYL-SUBSTITUTED BENZYL ORGANOTIN COMPOUND | BRIDGESTONE CORP | 1994-09-20 | — | — | JP | disclosed |