Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446590 | 0.94 | TP53 (0.41) | TP53TDP1LPLLIPGDRD2 | |
| SCHEMBL8519552 | 0.80 | LPL (0.53) | TP53TDP1LPLLIPGMEN1 | |
| SCHEMBL488957 | 0.80 | LPL (0.53) | TP53TDP1LPLLIPGMEN1 | |
| SCHEMBL489093 | 0.80 | LPL (0.53) | TP53TDP1LPLLIPGMEN1 | |
| SCHEMBL5036861 | 0.78 | LPL (0.51) | TP53TDP1LPLLIPG | |
| SCHEMBL489025 | 0.76 | TP53 (0.47) | TP53TDP1LPLLIPGMAPK1 | |
| SCHEMBL30540423 | 0.76 | TP53 (0.47) | TP53TDP1LPLLIPGMAPK1 | |
| SCHEMBL15529932 | 0.76 | DNM1 (0.50) | TP53DNM1MEN1KMT2AMAPK1 | |
| SCHEMBL27294328 | 0.75 | SIGMAR1 (0.45) | TP53TDP1DRD2OPRM1DRD3 | |
| Hydrochloric Acid SCHEMBL4576476 | 0.74 | KMT2A (0.61) | TP53TDP1LPLLIPGDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506319-A | LOW HYSTERESIS LOW, ABRASION RESISTANCE, WET SKID RESISTANCE | BRIDGESTONE CORPORATION (JP) | 1996-04-09 | — | — | US | claimed |
| EP-1184412-B1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | BRIDGESTONE CORP (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6822027-B2 | MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. | BRIDGESTONE CORPORATION (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20020049294-A1 | Rubber composition and heavy duty pneumatic tire using the rubber composition | BRIDGESTONE CORPORATION | 2002-04-25 | — | — | US | disclosed |
| EP-1184412-A1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | Bridgestone Corporation (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5506319-A | LOW HYSTERESIS LOW, ABRASION RESISTANCE, WET SKID RESISTANCE | BRIDGESTONE CORPORATION (JP) | 1996-04-09 | — | — | US | disclosed |