SCHEMBL8519552

SCHEMBL8519552

C=Cc1cccc(CCCCCCCCCCCC)c1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.53
LIPG Q9Y5X9 3/20 0.53
PPARA Q07869 4/20 0.46
PPARG P37231 3/20 0.46
TP53 P04637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
THRA P10827 3/20 0.44
THRB P10828 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL488957 1.00 LPL (0.53) LPLLIPGPPARAPPARGTP53
SCHEMBL489093 1.00 LPL (0.53) LPLLIPGPPARAPPARGTP53
SCHEMBL5036861 0.98 LPL (0.51) LPLLIPGPPARAPPARGTP53
SCHEMBL489025 0.93 TP53 (0.47) LPLLIPGPPARAPPARGTP53
SCHEMBL30540423 0.93 TP53 (0.47) LPLLIPGPPARAPPARGTP53
SCHEMBL595251 0.91 TP53 (0.47) LPLLIPGTP53TDP1
SCHEMBL29253203 0.87 LIPG (0.43) LPLLIPGPPARAPPARGTHRA
SCHEMBL488945 0.85 TP53 (0.50) LPLLIPGTP53TDP1THRB
SCHEMBL30257186 0.85 TP53 (0.50) LPLLIPGTP53TDP1THRB
SCHEMBL2921023 0.84 LPL (0.54) LPLLIPGPPARAPPARGTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113329890-A Bis-silylamino-functionalized conjugated diolefins, their preparation and their use in the production of rubbers 西索斯公司 2021-08-31 CN claimed
CN-110382509-B Bis-silylaminosilyl-functionalized conjugated dienes and their use in the manufacture of rubber 西索斯卓里第七公司 2021-08-10 CN claimed
CN-111971316-A Mixtures of aminosilyl-functionalized styrenes, their preparation and their use in the production of elastomeric copolymers 西索斯公司 2020-11-20 CN claimed
CN-107849194-B Elastomeric copolymers based on [ bis (trihydrocarbylsilyl) aminosilyl ] functionalized styrene and their use in the preparation of rubber 西索斯公司 2020-09-04 CN claimed
EP-0703505-B1 Toner for two-component type developer MITA INDUSTRIAL CO LTD (JP) 1999-07-14 EP disclosed
US-5750301-A BINDER RESINS WITH ANIONIC GROUPS AND GRAFTED WAX WITH MAGNETIC POWDERS MITA INDUSTRIAL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0703505-A1 Toner for two-component type developer MITA INDUSTRIAL CO., LTD. (JP) 1996-03-27 EP disclosed
EP-0379566-B1 LUBRICATING OIL COMPOSITIONS LUBRIZOL CORP (US) 1994-11-09 EP disclosed
US-4145490-A Carboxylated copolymers of isobutylene and a vinylbenzene E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-03-20 US disclosed
US-4031168-A ADHESIVES, FILMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-21 US disclosed