Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472383 | 0.93 | PDCD1 (0.32) | PDCD1CD274ALDH1A1POLBKCNA5 | |
| SCHEMBL6447588 | 0.77 | ALDH1A1 (0.41) | ALDH1A1POLB | |
| SCHEMBL28567795 | 0.76 | HTR2A (0.32) | PDCD1CD274TDO2HTR2A | |
| SCHEMBL29503364 | 0.76 | HTR2A (0.32) | PDCD1CD274TDO2HTR2A | |
| SCHEMBL31275339 | 0.75 | TDO2 (0.47) | PDCD1CD274TDO2HTR2A | |
| SCHEMBL2306813 | 0.75 | TDO2 (0.47) | PDCD1CD274TDO2HTR2A | |
| SCHEMBL6445670 | 0.73 | HTR2A (0.37) | TDO2HTR2A | |
| SCHEMBL5837267 | 0.72 | GPR3 (0.46) | ALDH1A1POLBGPR3HTR2A | |
| SCHEMBL6445406 | 0.71 | SLC22A2 (0.31) | — | |
| SCHEMBL28624583 | 0.67 | BCHE (0.37) | PDCD1CD274ALDH1A1GPR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065018-A1 | Preparation and use of heterogeneous catalyst components for olefins polymerization | (1) REPSOL QUIMICA S.A. | 2005-03-24 | — | — | US | disclosed |
| EP-0953580-B1 | Preparation and use of heterogeneous catalyst components for olefins polymerization | REPSOL QUIMICA SA (ES) | 2004-04-14 | — | — | EP | disclosed |
| US-20030144135-A1 | PREPARATION AND USE OF HETEROGENEOUS CATALYST COMPONENTS FOR OLEFINS POLYMERIZATION | REPSOL QUIMICA S.A. (ES) | 2003-07-31 | — | — | US | disclosed |
| EP-0955306-B1 | Functionalized metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA SA (ES) | 2003-01-22 | — | — | EP | disclosed |
| US-6114555-A | Functionalized metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA S.A. (ES) | 2000-09-05 | — | — | US | disclosed |
| EP-0955306-A1 | Functionalized metallocene compounds, synthesis process and use thereof | REPSOL QUIMICA S.A. (ES) | 1999-11-10 | — | — | EP | disclosed |
| EP-0953580-A1 | Preparation and use of heterogeneous catalyst components for olefins polymerization | REPSOL QUIMICA S.A. (ES) | 1999-11-03 | — | — | EP | disclosed |