SCHEMBL6446758

SCHEMBL6446758

COc1cc(C=O)c(O)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 16/20 0.45
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
TRIM24 O15164 1/20 0.42
TYR P14679 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TRPV1 Q8NER1 1/20 0.40
HSD17B10 Q99714 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3241119 0.82 ESR1 (0.44) ERN1TRIM24TRIM33ALDH1A1CYP3A4
SCHEMBL30829189 0.82 ESR1 (0.44) ERN1TRIM24TRIM33ALDH1A1CYP3A4
SCHEMBL15771550 0.81 ALOX5 (0.48) ERN1TRIM24TRIM33ALDH1A1KDM4E
SCHEMBL1685305 0.81 ERN1 (0.53) ERN1CA2TRIM24TYRTRIM33
SCHEMBL30186532 0.81 CA1 (0.67) ERN1CA1CA2TRIM24TYR
SCHEMBL311610 0.81 CA1 (0.67) ERN1CA1CA2TRIM24TYR
SCHEMBL2197374 0.80 ERN1 (0.51) ERN1ALDH1A1MEN1CYP3A4MAPT
SCHEMBL1685290 0.76 ERN1 (0.47) ERN1CA1CA2TRIM24TRIM33
SCHEMBL28224720 0.76 ALDH1A1 (0.51) CA1CA2ALDH1A1KDM4EMEN1
SCHEMBL7285302 0.75 ERN1 (0.62) ERN1TRIM24TYRTRIM33ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107501444-B Supported phenoxy imine polyolefin catalyst, preparation method and application 上海化工研究院有限公司 2020-09-11 CN disclosed
US-6962890-B2 Olefin polymerization catalyst and process for olefin polymerization using the olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2005-11-08 US disclosed
CN-1208356-C Olefine polymerization catalyst, and olefine polymerization method therewith MITSUI CHEMICAL IND CO LTD (JP) 2005-06-29 CN disclosed
EP-1013674-B1 Olefin polymerization catalyst and process for olefin polymerization using this catalyst MITSUI CHEMICALS INC (JP) 2005-04-27 EP disclosed
US-20030004290-A1 Olefin polymerization catalyst and process for olefin polymerization using the olefin polymerization catalyst MITSUI CHEMICALS, INC. 2003-01-02 US disclosed
CN-1259527-A Olefine polymerization catalyst, and olefine polymerization method therewith MITSUI CHEMICAL IND CO LTD (JP) 2000-07-12 CN disclosed
EP-1013674-A1 Olefin polymerization catalyst and process for olefin polymerization using this catalyst Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed