Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6520728 | 0.87 | ALDH1A1 (0.33) | ALDH1A1NOTUMHPGDMEN1KMT2A | |
| SCHEMBL2964749 | 0.83 | HPGD (0.32) | ALDH1A1NOTUMGAAGSK3AGSK3B | |
| SCHEMBL6442563 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NOTUMGAAGSK3AGSK3B | |
| SCHEMBL5974667 | 0.76 | ALDH1A1 (0.40) | ALDH1A1NOTUMGAAGSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL1071449 | 0.75 | ALDH1A1 (0.39) | ALDH1A1NOTUMHPGDMEN1KMT2A | |
| SCHEMBL6442527 | 0.70 | NOTUM (0.39) | ALDH1A1NOTUMGAAHPGDMEN1 | |
| SCHEMBL17996872 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL6519202 | 0.67 | ALDH1A1 (0.35) | ALDH1A1NOTUMHPGDMEN1KMT2A | |
| SCHEMBL18011739 | 0.64 | MAPT (0.47) | ALDH1A1NOTUMMEN1KMT2AMAPT | |
| SCHEMBL6547997 | 0.64 | MAPT (0.35) | ALDH1A1GAAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082363-A1 | ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE | Basell Polyolefine GmbH (DE) | 2001-03-14 | — | — | EP | claimed |
| WO-2000044799-A1 | ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE | TARGOR GMBH (DE) | 2000-08-03 | — | — | WO | claimed |
| US-9896519-B2 | Metallocene complex, preparation method thereof and catalyst composition | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2018-02-20 | — | — | US | disclosed |
| US-9896519-B2 | Metallocene complex, preparation method thereof and catalyst composition | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2018-02-20 | — | — | US | disclosed |
| EP-3056505-A1 | METALLOCENE COMPLEX, PREPARATION METHOD THEREFOR, AND CATALYST COMPOSITION | Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) | 2016-08-17 | — | — | EP | disclosed |
| US-20160229928-A1 | METALLOCENE COMPLEX, PREPARATION METHOD THEREOF AND CATALYST COMPOSITION | Changchun Institute of Chemistry, Chinese Academy of Sciences (CN) | 2016-08-11 | — | — | US | disclosed |
| US-20160229928-A1 | METALLOCENE COMPLEX, PREPARATION METHOD THEREOF AND CATALYST COMPOSITION | Changchun Institute of Chemistry, Chinese Academy of Sciences (CN) | 2016-08-11 | — | — | US | disclosed |
| EP-1272532-B1 | SALINE CHEMICAL COMPOSITION, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2005-05-04 | — | — | EP | disclosed |
| EP-1175262-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1290002-B1 | CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-01-21 | — | — | EP | disclosed |
| EP-1290002-A1 | CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001048035-A2 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| EP-1082363-A1 | ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE | Basell Polyolefine GmbH (DE) | 2001-03-14 | — | — | EP | disclosed |
| EP-1054914-A1 | ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND | Basell Polyolefine GmbH (DE) | 2000-11-29 | — | — | EP | disclosed |
| WO-2000064906-A1 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE IN A CATALYST SYSTEM FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |
| WO-2000062928-A1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2000-10-26 | — | — | WO | disclosed |
| WO-2000020466-A9 | CATALYST SYSTEM | TARGOR GMBH (DE) | 2000-09-21 | — | — | WO | disclosed |
| WO-2000044799-A1 | ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE | TARGOR GMBH (DE) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000035973-A1 | ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND WHICH CONTAINS BORON | TARGOR GMBH (DE) | 2000-06-22 | — | — | WO | disclosed |
| WO-2000018773-A1 | CHEMICAL COMPOUND | TARGOR GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229928-A1 | METALLOCENE COMPLEX, PREPARATION METHOD THEREOF AND CATALYST COMPOSITION | EMC1, COPS4, ELP1 | ALDH1A1 1031/4885NOTUM 979/4885GAA 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.