Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | PRKACG | P22612 | 1/20 | 0.40 |
| ▸ | PRKACB | P22694 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 6/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23674808 | 0.76 | ALDH1A1 (0.41) | LCKPRKACAPRKACGPRKACBERN1 | |
| SCHEMBL3814337 | 0.75 | ERN1 (0.37) | LCKERN1CA1CA2PTPN1 | |
| SCHEMBL22336337 | 0.75 | ALOX5 (0.41) | LCKPRKACAPRKACGPRKACBALOX5 | |
| SCHEMBL5760032 | 0.73 | TYR (0.53) | ERN1KDM4EGAATRIM24TYR | |
| SCHEMBL1119249 | 0.73 | ALOX5 (0.54) | LCKPRKACAPRKACGPRKACBALOX5 | |
| SCHEMBL931983 | 0.72 | ERN1 (0.60) | ERN1TRIM24TYRTRIM33 | |
| SCHEMBL2928368 | 0.71 | HTT (0.58) | GAACA1CA2THRBMEN1 | |
| SCHEMBL28963070 | 0.71 | HTT (0.58) | GAACA1CA2THRBMEN1 | |
| SCHEMBL1162537 | 0.71 | ALDH1A1 (0.46) | ERN1ALOX5PTGS2ABL1BCR | |
| SCHEMBL20551547 | 0.70 | HTT (0.42) | ERN1CA1CA2TRIM24TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-A1 | NOVEL CB 1 RECEPTOUR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004060870-A1 | NOVEL CB 1 RECEPTOUR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-22 | — | — | WO | disclosed |