Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834390 | 0.76 | EPHX1 (0.40) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL13619070 | 0.74 | SHBG (0.56) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL904038 | 0.74 | EPHX1 (0.56) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL4654285 | 0.72 | EPHX1 (0.55) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL9213980 | 0.72 | EPHX1 (0.42) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL23082587 | 0.70 | — | — | |
| SCHEMBL11698385 | 0.70 | — | — | |
| SCHEMBL3263270 | 0.70 | EPHX1 (0.40) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL21175606 | 0.70 | SHBG (0.46) | EPHX1SHBGTP53LMNAKDM4E | |
| SCHEMBL7285053 | 0.70 | EPHX1 (0.36) | EPHX1SHBGTP53LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172870-B | Polyhedral oligomeric silsesquioxane (POSS) modified double-bond containing elastomer and preparation method thereof | UNIV BEIJING CHEMICAL | 2015-04-29 | — | — | CN | claimed |
| CN-103172870-A | Polyhedral oligomeric silsesquioxane (POSS) modified double-bond containing elastomer and preparation method thereof | UNIV BEIJING CHEMICAL | 2013-06-26 | — | — | CN | claimed |
| CN-105367599-B | A kind of 3- cyclohexyl thio -1- propyl-triethoxysilane and its preparation method and application | 山东阳谷华泰化工股份有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-103172870-B | Polyhedral oligomeric silsesquioxane (POSS) modified double-bond containing elastomer and preparation method thereof | UNIV BEIJING CHEMICAL | 2015-04-29 | — | — | CN | disclosed |
| CN-103172870-A | Polyhedral oligomeric silsesquioxane (POSS) modified double-bond containing elastomer and preparation method thereof | UNIV BEIJING CHEMICAL | 2013-06-26 | — | — | CN | disclosed |
| US-8362264-B2 | Tryptophan antagonist; anticancer agents | DENDREON CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| CN-1239642-C | Anthraquinone compound and aqueous ink for inkjet recording using the same | MITSUI CHEMICALS INC (JP) | 2006-02-01 | — | — | CN | disclosed |
| CN-1218001-C | Yellow toner compound and aqueous ink for ink-jet recording apparatus using the same | MITSUI CHEMICALS INC (JP) | 2005-09-07 | — | — | CN | disclosed |
| US-20050054651-A1 | Compositions and methods for the treatment of disease associated with Trp-p8 expression | DENDREON CORPORATION (US) | 2005-03-10 | — | — | US | disclosed |
| CN-1366543-A | Anthraquinone compound and aqueous ink for inkjet recording using the same | MITSUI CHEMICALS INC (JP) | 2002-08-28 | — | — | CN | disclosed |
| CN-1322227-A | Yellow toner compound and aqueous ink for ink-jet recording apparatus using the same | MITSUI CHEMICALS INC (JP) | 2001-11-14 | — | — | CN | disclosed |
| CN-1110875-A | Fluorenone derivatives, process for preparing the same and central or peripheral nerve degeneration repair and protective agent | OTSUKA PHARMA CO LTD (JP) | 1995-10-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054651-A1 | Compositions and methods for the treatment of disease associated with Trp-p8 expression | TRPC4, TRPC3, TRPC1 | EPHX1 2270/4885SHBG 3730/4885TP53 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.