Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560171 | 0.93 | HMGB1 (0.57) | HMGB1PTPN1PTPN2PTPN6ALDH1A1 | |
| SCHEMBL2473330 | 0.92 | HMGB1 (0.56) | HMGB1PTPN1PTPN2PTPN6ALDH1A1 | |
| SCHEMBL15959651 | 0.88 | TSHR (0.58) | HMGB1PTPN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29697016 | 0.88 | HMGB1 (0.67) | HMGB1PTPN1PTPN2PTPN6ALDH1A1 | |
| SCHEMBL633197 | 0.88 | HMGB1 (0.67) | HMGB1PTPN1PTPN2PTPN6ALDH1A1 | |
| SCHEMBL8579457 | 0.84 | LMNA (0.46) | ALDH1A1KDM4EHPGDTSHRCYP2C9 | |
| SCHEMBL1396288 | 0.83 | HPGD (0.62) | HMGB1PTPN1PTPN2PTPN6ALDH1A1 | |
| SCHEMBL1161183 | 0.83 | HMGB1 (0.57) | HMGB1PTPN1PTPN2PTPN6ALDH1A1 | |
| SCHEMBL2467709 | 0.81 | HMGB1 (0.56) | HMGB1PTPN1PTPN2PTPN6ALDH1A1 | |
| SCHEMBL112902 | 0.81 | PTPN1 (0.65) | HMGB1PTPN1PTPN2PTPN6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238961-B1 | Process for the preparation of benzyl esters of hydroxybenzoic acids | BAYER CHEMICALS AG (DE) | 2005-01-26 | — | — | EP | disclosed |
| EP-1238961-A1 | Process for the preparation of benzyl esters of hydroxybenzoic acids | Bayer Aktiengesellschaft (DE) | 2002-09-11 | — | — | EP | disclosed |