⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259932 | 0.59 | — | — | |
| SCHEMBL23292983 | 0.58 | ALDH1A1 (0.30) | — | |
| SCHEMBL28001962 | 0.57 | — | — | |
| SCHEMBL9757638 | 0.56 | OPRM1 (0.34) | — | |
| SCHEMBL851567 | 0.56 | CHKA (0.50) | — | |
| SCHEMBL7190881 | 0.55 | — | — | |
| SCHEMBL4853981 | 0.54 | — | — | |
| SCHEMBL10423895 | 0.54 | — | — | |
| SCHEMBL8488894 | 0.54 | — | — | |
| SCHEMBL9813262 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6932961-B1 | Oxazinocarbazoles for the treatment of CNS diseases | PHARMACIA & UPJOHN COMPANY (US) | 2005-08-23 | — | — | US | disclosed |
| EP-1495031-A1 | LABELED OXAZINOCARBAZOLES AS DIAGNOSTIC AGENTS | Pharmacia & Upjohn Company LLC (US) | 2005-01-12 | — | — | EP | disclosed |
| US-6821970-B2 | USEFUL FOR TREATING DISEASES WHEREIN MODULATION OF 5-HT ACTIVITY IS DESIRED; NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY | 2004-11-23 | — | — | US | disclosed |
| WO-2003089438-A1 | LABELED OXAZINOCARBAZOLES AS DIAGNOSTIC AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2003-10-30 | — | — | WO | disclosed |
| EP-1200447-B1 | OXAZINOCARBAZOLES FOR THE TREATMENT OF CNS DISEASES | UPJOHN CO (US) | 2003-10-01 | — | — | EP | disclosed |
| US-20020169317-A1 | Oxazinocarbazoles for the treatment of CNS diseases | TENBRINK RUTH ELIZABETH (US) | 2002-11-14 | — | — | US | disclosed |
| US-6448397-B1 | TREATING CENTRAL NERVOUS SYSTEM DISEASES WITH MODULATION OF 5-HT ACTIVITY; ADRENERGIC, DOPAMINERGIC, AND SEROTONERGIC NEUROTRANSMITTERS; PSYCHOSIS, PARAPHRENIA, DEPRESSION, MANIA, SCHIZOPHRENIA, ANXIETY, MIGRAINE HEADACHE, DRUG ADDICTION | PHARMACIA & UPJOHN COMPANY | 2002-09-10 | — | — | US | disclosed |
| EP-1200447-A1 | OXAZINOCARBAZOLES FOR THE TREATMENT OF CNS DISEASES | PHARMACIA & UPJOHN COMPANY (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009142-A1 | OXAZINOCARBAZOLES FOR THE TREATMENT OF CNS DISEASES | PHARMACIA & UPJOHN COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |