Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135325 | 0.78 | OPRM1 (0.41) | OPRM1OPRD1OPRK1CHKAGRIN2D | |
| SCHEMBL9450404 | 0.78 | ALDH1A1 (0.37) | OPRM1OPRD1OPRK1CHKAGRIN2D | |
| SCHEMBL9160128 | 0.78 | ALDH1A1 (0.37) | OPRM1OPRD1OPRK1CHKAGRIN2D | |
| SCHEMBL1509676 | 0.74 | KDM4E (0.45) | OPRM1OPRD1OPRK1CHKAGRIN2D | |
| SCHEMBL10694157 | 0.74 | CHKA (0.41) | OPRM1OPRD1OPRK1CHKAGRIN2D | |
| SCHEMBL1509825 | 0.73 | KDM4E (0.39) | OPRM1OPRD1OPRK1CHKAGRIN2D | |
| SCHEMBL9861522 | 0.71 | ALDH1A1 (0.42) | OPRM1OPRD1OPRK1ALDH1A1LMNA | |
| SCHEMBL1688846 | 0.71 | CRHR1 (0.40) | OPRK1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL1509706 | 0.71 | C5AR1 (0.32) | OPRM1OPRD1OPRK1 | |
| SCHEMBL4557934 | 0.71 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999441-A | Tetrakis(dialkylamino)aromatics and their charge transfer complexes | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1991-03-12 | — | — | US | claimed |
| EP-0260646-A2 | Tetrakis (dialkylamino) aromatics and their charge transfer complexes | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1988-03-23 | — | — | EP | claimed |