SCHEMBL6447663

SCHEMBL6447663

COc1ccc(O)c(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.50
KMT2A Q03164 6/20 0.49
RARB P10826 5/20 0.49
MEN1 O00255 5/20 0.49
RARA P10276 4/20 0.49
RARG P13631 4/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GAA P10253 3/20 0.47
POLB P06746 1/20 0.47
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29191343 0.83 CNR2 (0.49) CNR2KMT2ARARBMEN1RARA
SCHEMBL3235386 0.81 KMT2A (0.44) CNR2KMT2ARARBMEN1RARA
SCHEMBL4748043 0.81 KMT2A (0.43) CNR2KMT2ARARBMEN1RARA
SCHEMBL9763566 0.81 KMT2A (0.43) CNR2KMT2ARARBMEN1RARA
SCHEMBL9763559 0.79 KMT2A (0.42) CNR2KMT2ARARBMEN1RARA
SCHEMBL7904172 0.79 KMT2A (0.48) CNR2KMT2ARARBMEN1RARA
SCHEMBL6878528 0.79 KMT2A (0.51) CNR2KMT2ARARBMEN1RARA
SCHEMBL18043698 0.79 CNR2 (0.48) CNR2KMT2ARARBMEN1RARA
SCHEMBL18043697 0.79 CNR2 (0.48) CNR2KMT2ARARBMEN1RARA
SCHEMBL27906875 0.78 CNR2 (0.40) CNR2KMT2ARARBMEN1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6962890-B2 Olefin polymerization catalyst and process for olefin polymerization using the olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2005-11-08 US disclosed
CN-1208356-C Olefine polymerization catalyst, and olefine polymerization method therewith MITSUI CHEMICAL IND CO LTD (JP) 2005-06-29 CN disclosed
EP-1013674-B1 Olefin polymerization catalyst and process for olefin polymerization using this catalyst MITSUI CHEMICALS INC (JP) 2005-04-27 EP disclosed
US-20030004290-A1 Olefin polymerization catalyst and process for olefin polymerization using the olefin polymerization catalyst MITSUI CHEMICALS, INC. 2003-01-02 US disclosed
CN-1259527-A Olefine polymerization catalyst, and olefine polymerization method therewith MITSUI CHEMICAL IND CO LTD (JP) 2000-07-12 CN disclosed
EP-1013674-A1 Olefin polymerization catalyst and process for olefin polymerization using this catalyst Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0629604-B1 Alicyclic phospholipase A2 inhibitors BRISTOL MYERS SQUIBB CO (US) 1997-04-16 EP disclosed
US-5436369-A Alicyclic phospholipase A2 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1995-07-25 US disclosed
CN-1099380-A Alicyclic phospholipase A2 inhibitors BRISTOL MYERS SQUIBB CO (US) 1995-03-01 CN disclosed
EP-0629604-A2 Alicyclic phospholipase A2 inhibitors Bristol-Myers Company (US) 1994-12-21 EP disclosed