Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447663 | 0.79 | CNR2 (0.50) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL4748043 | 0.79 | KMT2A (0.43) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL9763566 | 0.79 | KMT2A (0.43) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL18043697 | 0.78 | CNR2 (0.48) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL18043698 | 0.78 | CNR2 (0.48) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL5613344 | 0.77 | PPARG (0.44) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL3235386 | 0.77 | KMT2A (0.44) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL11783889 | 0.76 | ALDH1A1 (0.49) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL4492866 | 0.75 | KMT2A (0.43) | KMT2ACNR2LMNATDP1KDM4E | |
| SCHEMBL7904172 | 0.75 | KMT2A (0.48) | KMT2ACNR2LMNATDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015758-A | Process for the preparation of 1-adamantane derivatives | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1991-05-14 | — | — | US | disclosed |