Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498644 | 0.78 | PDE5A (0.38) | MAPTGAAKDM4EMEN1LMNA | |
| SCHEMBL9377442 | 0.75 | KDM4E (0.47) | MAPTGAAKDM4ELMNATDO2 | |
| SCHEMBL570948 | 0.75 | KDM4E (0.47) | MAPTGAAKDM4ELMNATDO2 | |
| SCHEMBL8786474 | 0.75 | KDM4E (0.47) | MAPTGAAKDM4ELMNATDO2 | |
| SCHEMBL4849477 | 0.75 | KDM4E (0.47) | MAPTGAAKDM4ELMNATDO2 | |
| SCHEMBL990901 | 0.75 | MAPT (0.47) | MAPTGAAKDM4EMEN1LMNA | |
| SCHEMBL8897147 | 0.75 | MAPT (0.45) | MAPTGAAKDM4EMEN1LMNA | |
| SCHEMBL22646205 | 0.75 | MAPT (0.45) | MAPTGAAKDM4EMEN1LMNA | |
| SCHEMBL23071358 | 0.74 | NPY5R (0.44) | MAPTGAAMEN1LMNAKMT2A | |
| SCHEMBL1067058 | 0.73 | KDM4E (0.44) | MAPTGAAKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1536847-A1 | RADIATION STERILIZED MEDICAL DEVICES COMPRISING RADIATION SENSITIVE POLYMERS | SCIMED LIFE SYSTEMS, INC. (US) | 2005-06-08 | — | — | EP | claimed |
| WO-2004024204-A1 | RADIATION STERILIZED MEDICAL DEVICES COMPRISING RADIATION SENSITIVE POLYMERS | SCIMED LIFE SYSTEMS, INC. (US) | 2004-03-25 | — | — | WO | claimed |