SCHEMBL570948

SCHEMBL570948

Nc1ccccc1C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
NOS1 P29475 3/20 0.43
TDO2 P48775 2/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.42
PTGS2 P35354 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
KEAP1 Q14145 1/20 0.38
NOS3 P29474 1/20 0.36
NOS2 P35228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8786474 1.00 KDM4E (0.47) KDM4EGAAMAPTNOS1TDO2
SCHEMBL9377442 1.00 KDM4E (0.47) KDM4EGAAMAPTNOS1TDO2
SCHEMBL4849477 1.00 KDM4E (0.47) KDM4EGAAMAPTNOS1TDO2
SCHEMBL1067058 0.98 KDM4E (0.44) KDM4EGAAMAPTNOS1TDO2
SCHEMBL1068978 0.93 NOS1 (0.41) KDM4EGAAMAPTNOS1TDO2
SCHEMBL744815 0.88 ALOX15 (0.45) KDM4EGAAMAPTSMN1; SMN2CYP3A4
SCHEMBL27569418 0.86 PTGS2 (0.43) KDM4EGAAMAPTNOS1TDO2
SCHEMBL27449541 0.83 KDM4E (0.39) KDM4EGAAMAPTTDO2PTGDR2
SCHEMBL27515908 0.83 KDM4E (0.39) KDM4EGAAMAPTTDO2PTGDR2
Trifluoroacetic Acid SCHEMBL5189043 0.83 PTGDR2 (0.46) GAAPTGDR2PTGS2HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512830-B1 METHOD FOR THE HYDROGENATION OF A MIXTURE IN THE PRESENCE OF A COLOURLESS AMINE BASF SE (DE) 2025-03-12 EP claimed
CN-119114095-A Method for recycling industrial aniline waste liquid 万华化学集团股份有限公司 2024-12-13 CN claimed
EP-3995492-B1 A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES SpecGx LLC (US) 2024-05-29 EP claimed
CN-112898170-B Preparation method of acid diffusion inhibitor and photoresist composition 宁波南大光电材料有限公司 2022-10-04 CN claimed
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP claimed
CN-114057623-A N-naphthyl indole derivative and synthetic method thereof 湖南第一师范学院 2022-02-18 CN claimed
CN-112898170-A Preparation method of acid diffusion inhibitor and photoresist composition 宁波南大光电材料有限公司 2021-06-04 CN claimed
US-10927066-B2 Process for hydrogenating a mixture in the presence of a colorless amine BASF SE (DE) 2021-02-23 US claimed
CN-110172058-A 7- azaspiro [5.6] dodecane -10- ketone compounds and preparation method thereof and purposes 中国医科大学 2019-08-27 CN claimed
US-20190210955-A1 PROCESS FOR HYDROGENATING A MIXTURE IN THE PRESENCE OF A COLORLESS AMINE BASF SE (DE) 2019-07-11 US claimed
EP-1428857-B1 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ARKEMA FRANCE (FR) 2007-01-31 EP claimed
US-7091381-B2 Process for preparation of cyclohexanone oxime ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-08-15 US claimed
WO-2006047503-A2 INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA (BE) 2006-05-04 WO claimed
US-20050113566-A1 Inhibitors of C-FMS kinase JANSSEN PHARMACEUTICA N.V. (BE) 2005-05-26 US claimed
CN-1533375-A Process for producing cyclohexanone oxime ɻ�ѧ��ʽ���� 2004-09-29 CN claimed
US-20040176592-A1 Process for preparation of cyclohexanone oxime ASAHI KASEI CHEMICALS CORPORATION (JP) 2004-09-09 US claimed
US-6710008-B2 MAKING MOLECULAR SIEVE CATALYST FROM DRIED MOLECULAR SIEVE CATALYST PARTICLES. EXXONMOBIL CHEMICAL PATENTS INC. 2004-03-23 US claimed
EP-0813517-B1 HYDROGENATION OF UNSATURATED CYCLIC COMPOUNDS CHEMICAL RES & LICENSING CO (US) 2001-11-14 EP claimed
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US claimed
US-4410730-A Process for the production of o-(N-monosubstituted amino)benzyl alcohols SHIONOGI & CO., LTD. (JP) 1983-10-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113566-A1 Inhibitors of C-FMS kinase ALK, TYRO3, PDGFRB KDM4E 2647/4885GAA 3756/4885MAPT 4732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.