Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.56 |
| ▸ | CBR1 | P16152 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861651 | 0.83 | KMT2A (0.55) | MAPTHPGDSTK39ALDH1A1KMT2A | |
| SCHEMBL22407108 | 0.81 | MRGPRX4 (0.54) | TTRMAPTSLC6A2SLC6A3HPGD | |
| SCHEMBL364764 | 0.80 | ALDH1A1 (0.65) | MAPTHPGDLMNAALDH1A1POLB | |
| SCHEMBL9948495 | 0.80 | CYP1A2 (0.54) | HPGDLMNASTK39ALDH1A1GAA | |
| SCHEMBL7861800 | 0.80 | TTR (0.53) | TTRMAPTSLC6A2SLC6A3HPGD | |
| SCHEMBL7186092 | 0.79 | TTR (0.75) | TTRMAPTSLC6A2SLC6A3HPGD | |
| SCHEMBL3691064 | 0.79 | KMT2A (0.61) | MAPTHPGDLMNAALDH1A1GAA | |
| SCHEMBL9035058 | 0.79 | ESRRA (0.54) | TTRMAPTSLC6A2SLC6A3HPGD | |
| SCHEMBL2040582 | 0.78 | TTR (0.56) | TTRMAPTSLC6A2SLC6A3HPGD | |
| Triclosan SCHEMBL2043517 | 0.78 | TTR (0.80) | TTRMAPTSLC6A2SLC6A3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320516-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED HYDROXYDIPHENYL COMPOUNDS | CIBA SC HOLDING AG (CH) | 2005-10-05 | — | — | EP | disclosed |
| US-6706930-B2 | ACYLATION OF A HALOGENATED BENZENE COMPOUND, ETHERIFICATION OF ETHERIFICATION OF THE ACYLATED COMPOUND WITH A HALOGENATED PHENOL, OXIDATION OF THE ETHERIFIED COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-03-16 | — | — | US | disclosed |
| US-20030163005-A1 | Process for the preparation of halogenated hydroxydiphenyl compounds | CIBA SPECIALTY CHEMICALS CORP. | 2003-08-28 | — | — | US | disclosed |
| EP-1320516-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED HYDROXYDIPHENYL COMPOUNDS | Ciba SC Holding AG (CH) | 2003-06-25 | — | — | EP | disclosed |
| WO-2001083418-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED HYDROXYDIPHENYL COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-08 | — | — | WO | disclosed |
| EP-1007501-A1 | PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS | THE DOW CHEMICAL COMPANY (US) | 2000-06-14 | — | — | EP | disclosed |
| EP-1007501-A1 | PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS | THE DOW CHEMICAL COMPANY (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999010310-A1 | PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS | THE DOW CHEMICAL COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1999010310-A1 | PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS | THE DOW CHEMICAL COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030163005-A1 | Process for the preparation of halogenated hydroxydiphenyl compounds | CBR1, CYP1A1, AOC2 | TTR 3376/4885MAPT 4547/4885SLC6A2 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.