Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645747 | 0.83 | NPC1 (0.50) | HTR1AKCNH2DRD2HTR2AABL1 | |
| SCHEMBL645892 | 0.83 | DRD2 (0.52) | HTR1AKCNH2HTR7DRD2 | |
| SCHEMBL7927182 | 0.81 | ADRA2C (0.65) | BPTFADRA2CHTR6POLBKMT2A | |
| SCHEMBL24008617 | 0.80 | BPTF (0.58) | BPTFHTR1AKCNH2NPSR1HTR7 | |
| SCHEMBL30323093 | 0.80 | BPTF (0.58) | BPTFHTR1AKCNH2NPSR1HTR7 | |
| SCHEMBL12424927 | 0.80 | BPTF (0.64) | BPTFHTR1AHTR7DRD2HTR2A | |
| SCHEMBL3665721 | 0.80 | KCNH2 (0.61) | HTR1AKCNH2ADRA2CHTR7DRD2 | |
| SCHEMBL24572269 | 0.79 | DRD2 (0.51) | HTR1AKCNH2HTR7DRD2HTR2A | |
| SCHEMBL28706080 | 0.77 | BPTF (0.64) | BPTFHTR1AHTR7DRD2HTR2A | |
| SCHEMBL24834707 | 0.76 | MAPT (0.47) | KCNH2ADRA2CNPSR1DRD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119633-B2 | N-{2-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-2-oxo-ethoxy]-ethyl}-N-ethyl-4-methoxy-2,3,6-trimethyl-phenylsulfonamide; condensing the N-carboxyalkyl phenylsulfonamide with the substituted piperidine; bradykinin receptor antagonists; analgesics; antidiabetics; angiogenesis inhibitors; rheumatic diseases | GRUENENTHAL GMBH (DE) | 2012-02-21 | — | — | US | disclosed |